Gene Symbol | RBBP5 |
---|---|
Entrez Gene | 5929 |
Alt Symbol | RBQ3, SWD1 |
Species | Human |
Gene Type | protein-coding |
Description | retinoblastoma binding protein 5 |
Other Description | RBBP-5|SWD1, Set1c WD40 repeat protein, homolog|retinoblastoma-binding protein 5|retinoblastoma-binding protein RBQ-3 |
Swissprots | Q8NDZ7 Q7Z6D8 Q15291 A8K272 |
Accessions | EAW91536 EAW91537 EAW91538 EAW91539 Q15291 AA235403 AK290137 BAF82826 AK296978 BAG59520 AK297540 BAG59939 AU099032 BC037284 AAH37284 BC053856 AAH53856 BC075059 AAH75059 BC075060 AAH75060 BG392257 BQ020418 CB133829 CD710496 DA797022 DQ891205 ABM82131 DQ894388 ABM85314 X85134 CAA59446 XM_005245398 XP_005245455 XM_005245401 XP_005245458 XM_006711477 XP_006711540 XM_011509833 XP_011508135 XM_011509834 XP_011508136 NM_001193272 NP_001180201 NM_001193273 NP_001180202 NM_005057 NP_005048 |
Function | In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. {ECO:0000250, ECO:0000269|PubMed:19556245}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17355966}. |
Tissue Specificity | Ubiquitously expressed. |
Human RbBP5 full length protein - ab132195 from Abcam
|
||||||||||
Human RbBP5 full length protein - ab135017 from Abcam
|
||||||||||
RbBP5 peptide - ab87828 from Abcam
|
||||||||||
RBBP5 Antibody Blocking Peptide - LS-E12108 from LifeSpan Bioscience
|
||||||||||
RBBP5 Antibody Blocking Peptide - LS-E12109 from LifeSpan Bioscience
|
||||||||||
RBBP5 Antibody Blocking Peptide - LS-E13866 from LifeSpan Bioscience
|
||||||||||
Recombinant Human RbBP5 Protein - H00005929-P01 from Novus Biologicals
|
||||||||||
Recombinant Human RbBP5 Protein - H00005929-Q01 from Novus Biologicals
|
||||||||||
RbBP5 Blocking Peptide - 33R-10917 from Fitzgerald
|
||||||||||
RBBP5 Blocking Peptide - 33R-6849 from Fitzgerald
|
||||||||||
RBBP5 / RBQ3 - H00005929-P01-10 from Acris Antibodies
|
||||||||||
RBBP5 / RBQ3 - H00005929-P01-25 from Acris Antibodies
|
||||||||||
RBBP5 / RBQ3 - H00005929-Q01-10 from Acris Antibodies
|
||||||||||
RBBP5 / RBQ3 - H00005929-Q01-25 from Acris Antibodies
|
||||||||||
RBBP5 fusion protein - Ag3848 from Proteintech Group
|
||||||||||
RbBP5, Human recombinant protein - GWB-PSA30B from Genway Biotech
|
||||||||||
Recombinant Human RBBP5, His-tagged - RBBP5-28182TH from Creative Biomart
|
||||||||||
Recombinant Human RBBP5, GST-tagged - RBBP5-2199H from Creative Biomart
|
||||||||||
Recombinant Human Retinoblastoma-binding protein 5(RBBP5) - CSB-YP613589HU CSB-EP613589HU CSB-BP613589HU CSB-MP613589HU from Cusabio
|
||||||||||
RbBP5 Blocking Peptide - 3793RBP-50 from Biovision
|
||||||||||
RbBP5 Recombinant Protein Antigen - NBP2-34100PEP from Novus Biologicals
|
||||||||||
RBBP5 Antibody - SH-A15124 from Novatein Biosciences
|
||||||||||
RBBP5-Blocking-Peptide-C-term - BP20943c from Abgent, a WuXi AppTec company
|
||||||||||
RBBP5-Blocking-Peptide-C-term - BP21555b from Abgent, a WuXi AppTec company
|
||||||||||
RBBP5 Peptide, Human - M34GP13027H from Creative Peptides
|