RBBP5

Gene Symbol RBBP5
Entrez Gene 5929
Alt Symbol RBQ3, SWD1
Species Human
Gene Type protein-coding
Description retinoblastoma binding protein 5
Other Description RBBP-5|SWD1, Set1c WD40 repeat protein, homolog|retinoblastoma-binding protein 5|retinoblastoma-binding protein RBQ-3
Swissprots Q8NDZ7 Q7Z6D8 Q15291 A8K272
Accessions EAW91536 EAW91537 EAW91538 EAW91539 Q15291 AA235403 AK290137 BAF82826 AK296978 BAG59520 AK297540 BAG59939 AU099032 BC037284 AAH37284 BC053856 AAH53856 BC075059 AAH75059 BC075060 AAH75060 BG392257 BQ020418 CB133829 CD710496 DA797022 DQ891205 ABM82131 DQ894388 ABM85314 X85134 CAA59446 XM_005245398 XP_005245455 XM_005245401 XP_005245458 XM_006711477 XP_006711540 XM_011509833 XP_011508135 XM_011509834 XP_011508136 NM_001193272 NP_001180201 NM_001193273 NP_001180202 NM_005057 NP_005048
Function In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. {ECO:0000250, ECO:0000269|PubMed:19556245}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17355966}.
Tissue Specificity Ubiquitously expressed.

RBBP5 (D3I6P) Rabbit mAb - 13171 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3I6P
Western blot analysis of extracts from various cell lines using RBBP5 (D3I6P) Rabbit mAb.

RBBP5 Antibody - 8037 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using RBBP5 Antibody.

RBBP5 (D4Y7R) Rabbit mAb - 12766 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4Y7R
Western blot analysis of extracts from various cell lines using RBBP5 (D4Y7R) Rabbit mAb.

RBQ-3 (A-8) - sc-374481 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RBQ-3 (A-8): sc-374481. Western blot analysis of RBQ-3 expression in non-transfected: sc-117752 (A) and human RBQ-3 transfected: sc-116474 (B) 293T whole cell lysates.

RBQ-3 (F-7) - sc-271072 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RBQ-3 (F-7): sc-271072. Western blot analysis of RBQ-3 expression in Hep G2 whole cell lysate.

RBQ-3 (D-7) - sc-390954 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RBQ-3 (D-7): sc-390954. Western blot analysis of RBQ-3 expression in non-transfected: sc-117752 (A) and human RBQ-3 transfected: sc-116474 (B) 293T whole cell lysates.

RBQ-3 (K-20) - sc-79012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RBQ-3 (K-20): sc-79012. Western blot analysis of RBQ-3 expression in non-transfected: sc-117752 (A) and human RBQ-3 transfected: sc-116474 (B) 293T whole cell lysates.

RBQ-3 (D-6) - sc-271071 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RBQ-3 (D-6): sc-271071. Western blot analysis of RBQ-3 expression in Hep G2 whole cell lysate.

RBQ-3 (H-269) - sc-98551 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RBQ-3 (H-269): sc-98551. Western blot analysis of RBQ-3 expression in HeLa whole cell lysate.

RBQ-3 (C-18) - sc-79010 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RBQ-3 (C-18): sc-79010. Western blot analysis of RBQ-3 expression in non-transfected: sc-117752 (A) and human RBQ-3 transfected: sc-116474 (B) 293T whole cell lysates.

Anti-RbBP5 antibody - ab154755 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RbBP5 antibody (ab154755) at 1/500 dilution + A431 whole cell lysate at 30 µg

Anti-RbBP5 antibody - ab52084 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab52084 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab52084, 5µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-RbBP5 antibody - ab84511 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84511, at 1/250 dilution, staining RbBP5 in formalin-fixed, paraffin-embedded human colon adenocarcinoma by Immunohistochemistry, using DAB staining.

Anti-RbBP5 antibody - ab87190 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RbBP5 antibody (ab87190) at 1 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RbBP5 antibody - ab80074 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RbBP5 antibody (ab80074) at 1 µg/mlLane 1 : WERI (Human Retinoblastoma) Whole Cell Lysate Lane 2 : Y79 (Human retinoblastoma cell line) Whole Cell LysateLane 3 : SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate Lane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-RbBP5 antibody - ab168455 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RbBP5 antibody (ab168455) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with RbBP5Lane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µg per lane.developed using the ECL technique

Anti-RBBP5 Antibody - LS-C48715 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP5 Antibody - LS-C93689 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RBBP5 Antibody - LS-C131813 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RBBP5 Antibody - LS-C146956 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RBBP5 Antibody (aa324-373) - LS-C109877 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RBBP5 antibody LS-C109877 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-RBBP5 Antibody (aa431-480) - LS-C101484 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RBBP5 antibody LS-C101484 Western blot of HepG2 cell lysate.

Anti-RBBP5 Antibody (N-Terminus) - LS-C145859 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RBBP5 antibody LS-C145859 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

Anti-RBBP5 Antibody - LS-C346158 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of U20S cell using RBBP5 antibody. Blue: DAPI for nuclear staining.

Anti-RBBP5 Antibody (C-Terminus) - LS-C286431 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse RbBP5 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-RbBP5 used at a dilution of 1:250.
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