Gene Symbol | RBBP5 |
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Entrez Gene | 5929 |
Alt Symbol | RBQ3, SWD1 |
Species | Human |
Gene Type | protein-coding |
Description | retinoblastoma binding protein 5 |
Other Description | RBBP-5|SWD1, Set1c WD40 repeat protein, homolog|retinoblastoma-binding protein 5|retinoblastoma-binding protein RBQ-3 |
Swissprots | Q8NDZ7 Q7Z6D8 Q15291 A8K272 |
Accessions | EAW91536 EAW91537 EAW91538 EAW91539 Q15291 AA235403 AK290137 BAF82826 AK296978 BAG59520 AK297540 BAG59939 AU099032 BC037284 AAH37284 BC053856 AAH53856 BC075059 AAH75059 BC075060 AAH75060 BG392257 BQ020418 CB133829 CD710496 DA797022 DQ891205 ABM82131 DQ894388 ABM85314 X85134 CAA59446 XM_005245398 XP_005245455 XM_005245401 XP_005245458 XM_006711477 XP_006711540 XM_011509833 XP_011508135 XM_011509834 XP_011508136 NM_001193272 NP_001180201 NM_001193273 NP_001180202 NM_005057 NP_005048 |
Function | In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. {ECO:0000250, ECO:0000269|PubMed:19556245}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17355966}. |
Tissue Specificity | Ubiquitously expressed. |
RBBP5 (D3I6P) Rabbit mAb - 13171 from Cell Signaling Technology
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RBBP5 Antibody - 8037 from Cell Signaling Technology
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RBBP5 (D4Y7R) Rabbit mAb - 12766 from Cell Signaling Technology
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RBQ-3 (A-8) - sc-374481 from Santa Cruz Biotechnology
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RBQ-3 (F-7) - sc-271072 from Santa Cruz Biotechnology
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RBQ-3 (D-7) - sc-390954 from Santa Cruz Biotechnology
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RBQ-3 (K-20) - sc-79012 from Santa Cruz Biotechnology
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RBQ-3 (D-6) - sc-271071 from Santa Cruz Biotechnology
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RBQ-3 (H-269) - sc-98551 from Santa Cruz Biotechnology
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RBQ-3 (C-18) - sc-79010 from Santa Cruz Biotechnology
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Anti-RbBP5 antibody - ab154755 from Abcam
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Anti-RbBP5 antibody - ab52084 from Abcam
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Anti-RbBP5 antibody - ab84511 from Abcam
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Anti-RbBP5 antibody - ab87190 from Abcam
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Anti-RbBP5 antibody - ab80074 from Abcam
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Anti-RbBP5 antibody - ab168455 from Abcam
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Anti-RBBP5 Antibody - LS-C48715 from LifeSpan Bioscience
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Anti-RBBP5 Antibody - LS-C93689 from LifeSpan Bioscience
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Anti-RBBP5 Antibody - LS-C131813 from LifeSpan Bioscience
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Anti-RBBP5 Antibody - LS-C146956 from LifeSpan Bioscience
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Anti-RBBP5 Antibody (aa324-373) - LS-C109877 from LifeSpan Bioscience
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Anti-RBBP5 Antibody (aa431-480) - LS-C101484 from LifeSpan Bioscience
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Anti-RBBP5 Antibody (N-Terminus) - LS-C145859 from LifeSpan Bioscience
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Anti-RBBP5 Antibody - LS-C346158 from LifeSpan Bioscience
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Anti-RBBP5 Antibody (C-Terminus) - LS-C286431 from LifeSpan Bioscience
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