KLF17
| Gene Symbol | KLF17 |
|---|---|
| Entrez Gene | 128209 |
| Alt Symbol | ZNF393, Zfp393 |
| Species | Human |
| Gene Type | protein-coding |
| Description | Kruppel-like factor 17 |
| Other Description | Krueppel-like factor 17|novel zinc-finger protein|zinc finger protein 393 |
| Swissprots | Q86VQ7 Q8N805 Q5JT82 |
| Accessions | CBH30658 EAX07052 EAX07053 Q5JT82 AK097479 BAC05070 AK308458 BC031250 BC035408 BC049844 AAH49844 DB046781 HG491971 HG491972 HG491973 HG491974 HG491975 HG491977 LK938585 XM_005270465 XP_005270522 XM_011540700 XP_011539002 XM_011540701 XP_011539003 XM_011540702 XP_011539004 XM_011540703 XP_011539005 XM_011540704 XP_011539006 NM_173484 NP_775755 |
| Function | Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
KLF17-Over-expression-Lysate - LY15610a from Abgent, a WuXi AppTec company
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KLF17 overexpression lysate - LY406601 from Acris Antibodies
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KLF17 293 Cell Lysate - 403978 from ABBIOTEC
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KLF17 Overexpression Lysate (Native) - NBL1-12318 from Novus Biologicals
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KLF17 (h): 293T Lysate - sc-116004 from Santa Cruz Biotechnology
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KLF17 Over-expression Lysate Product - GWB-156371 from Genway Biotech
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Panoply™ Human KLF17 Knockdown Stable Cell Line - CSC-DC008249 from Creative biogene
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