Gene Symbol | KLF17 |
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Entrez Gene | 128209 |
Alt Symbol | ZNF393, Zfp393 |
Species | Human |
Gene Type | protein-coding |
Description | Kruppel-like factor 17 |
Other Description | Krueppel-like factor 17|novel zinc-finger protein|zinc finger protein 393 |
Swissprots | Q86VQ7 Q8N805 Q5JT82 |
Accessions | CBH30658 EAX07052 EAX07053 Q5JT82 AK097479 BAC05070 AK308458 BC031250 BC035408 BC049844 AAH49844 DB046781 HG491971 HG491972 HG491973 HG491974 HG491975 HG491977 LK938585 XM_005270465 XP_005270522 XM_011540700 XP_011539002 XM_011540701 XP_011539003 XM_011540702 XP_011539004 XM_011540703 XP_011539005 XM_011540704 XP_011539006 NM_173484 NP_775755 |
Function | Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human-KLF17-cDNA-Clone - DC07770 from Abgent, a WuXi AppTec company
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KLF17 - MBS1277531 from MyBioSource
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Human KLF17 cDNA clone(NM_173484.3) - CDFG010696 from Creative Biomart
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Human KLF17 ORF Clone(NM_173484.3) - CDCR321885 from Creative Biomart
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Human KLF17 ORF Clone(NM_173484.3) - CDCR321886 from Creative Biomart
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Human KLF17 ORF Clone(NM_173484.3) - CDCR321887 from Creative Biomart
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Human KLF17 ORF clone (NM_173484.3) - CDCL124589 from Creative biogene
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Human KLF17 ORF Clone (BC049844) - CDCS417391 from Creative biogene
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Human KLF17 cDNA Clone(NM_173484.3) - CDFG010696 from Creative biogene
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