Gene Symbol | CAPN6 |
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Entrez Gene | 827 |
Alt Symbol | CANPX, CAPNX, CalpM, DJ914P14.1 |
Species | Human |
Gene Type | protein-coding |
Description | calpain 6 |
Other Description | calpain-6|calpain-like protease X-linked|calpamodulin |
Swissprots | D3DUY7 Q9Y6Q1 Q9UJA8 Q9UEQ1 |
Accessions | AAV41896 CAB70568 EAX02650 EAX02651 Q9Y6Q1 AA368247 AF029232 AAB86605 AJ000388 CAA04051 AK300340 BAG62085 AK312701 BAG35579 BC000730 AAH00730 DA863483 DQ891851 ABM82777 DQ895041 ABM85967 L32067 NM_014289 NP_055104 |
Function | Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:17210638}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17210638}. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle. |
Tissue Specificity | Expressed only in placenta. |
Calpain 6 peptide - ab41314 from Abcam
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Calpain 6 peptide - ab41315 from Abcam
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CAPN6 / Calpain 6 Antibody Blocking Peptide - LS-E1754 from LifeSpan Bioscience
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CAPN6 / Calpain 6 Antibody Blocking Peptide - LS-E30554 from LifeSpan Bioscience
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Calpain 6 Blocking Peptide - NBP1-76937PEP from Novus Biologicals
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CAPN6-Antibody-Center-Blocking-peptide - BP12546c from Abgent, a WuXi AppTec company
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CAPN6 Peptide - GTX85383-PEP from GeneTex
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Calpain-6 Control Peptide - AP30177CP-N from Acris Antibodies
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CAPN6 Peptide - 4759P from ProSci
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CAPN6 fusion protein - ag0160 from Proteintech Group
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Calpain-6 Peptide - 350556 from ABBIOTEC
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Recombinant Human CAPN6, GST-tagged - CAPN6-10705H from Creative Biomart
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Recombinant Calpain 6 (CAPN6) - RPF255Hu01 from Uscn Life Science Inc.
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Recombinant Calpain 6 (CAPN6) - RPF255Hu01 from Cloud-clone
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Recombinant Human Calpain-6(CAPN6) - CSB-YP897594HU CSB-EP897594HU CSB-BP897594HU CSB-MP897594HU from Cusabio
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Calpain-6 - TP300539 from Acris Antibodies
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Calpain-6 (CAPN6), Recombinant Protein - MBS1418364 from MyBioSource
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CAPN6 Peptide, Human - M34GP02350H from Creative Peptides
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Recombinant Calpain 6 (CAPN6) - RPU53656 from Biomatik
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CAPN6 Recombinant Protein (OPCD00235) - OPCD00235 from Aviva Systems Biology
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Calpain 6, Recombinant Protein - MBS2034204 from MyBioSource
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