CAPN6

Gene Symbol CAPN6
Entrez Gene 827
Alt Symbol CANPX, CAPNX, CalpM, DJ914P14.1
Species Human
Gene Type protein-coding
Description calpain 6
Other Description calpain-6|calpain-like protease X-linked|calpamodulin
Swissprots D3DUY7 Q9Y6Q1 Q9UJA8 Q9UEQ1
Accessions AAV41896 CAB70568 EAX02650 EAX02651 Q9Y6Q1 AA368247 AF029232 AAB86605 AJ000388 CAA04051 AK300340 BAG62085 AK312701 BAG35579 BC000730 AAH00730 DA863483 DQ891851 ABM82777 DQ895041 ABM85967 L32067 NM_014289 NP_055104
Function Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:17210638}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17210638}. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle.
Tissue Specificity Expressed only in placenta.

Calpain 6 CRISPR/Cas9 KO Plasmid (h) - sc-407700 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 HDR Plasmid (h) - sc-407700-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 Double Nickase Plasmid (h) - sc-407700-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 Double Nickase Plasmid (h2) - sc-407700-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 CRISPR Activation Plasmid (h) - sc-407700-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 CRISPR Activation Plasmid (h2) - sc-407700-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 Lentiviral Activation Particles (h) - sc-407700-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 Lentiviral Activation Particles (h2) - sc-407700-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 6 siRNA (h) - sc-62066 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calpain 6 shRNA Plasmid (h) - sc-62066-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calpain 6 shRNA (h) Lentiviral Particles - sc-62066-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU028911 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2393 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2393 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09430 from Sigma-Aldrich

Category miRNA

CAPN6 siRNA (Human) - CRH0581 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CAPN6 - MBS8201324 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CAPN6 (NM_014289.3) - SHH254369 from Creative biogene

Category siRNA
Species Reactivities Human

Human CAPN6 siRNA - orb261083 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CAPN6 shRNA Plasmid (Human) - CHH0581 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CAPN6 miRNA 3'UTR clone - MiUTR3H-02597 from Creative biogene

Species Reactivities Human
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