RAB27A

Gene Symbol	RAB27A
Entrez Gene	5873
Alt Symbol	GS2, HsT18676, RAB27, RAM
Species	Human
Gene Type	protein-coding
Description	RAB27A, member RAS oncogene family
Other Description	GTP-binding protein Ram|rab-27|ras-related protein Rab-27A
Swissprots	Q9Y5U3 O00195 Q6FI40 P51159 Q9UIR9
Accessions	AAD47629 AAL39097 EAW77476 EAW77477 EAW77478 EAW77479 P51159 AF125393 AAD43049 AF498953 AAM21101 AK312836 BAG35690 AV661679 BC078139 BC107680 AAI07681 BC132800 AAI32801 BC136423 AAI36424 BM014705 CA398159 CA437806 CR457076 CAG33357 CR536496 CAG38735 CR541693 CAG46494 DA182503 DA553342 HQ258130 ADR82884 U38654 AAC50271 U57094 AAC51195 XM_005254576 XP_005254633 XM_011521852 XP_011520154 XM_011521853 XP_011520155 XM_011521854 XP_011520156 XM_011521855 XP_011520157 XM_011521856 XP_011520158 NM_004580 NP_004571 NM_183234 NP_899057 NM_183235 NP_899058 NM_183236 NP_899059
Function	Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. {ECO:0000269|PubMed:18812475}.
Subcellular Location	Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles.
Tissue Specificity	Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells. {ECO:0000269|PubMed:15548590}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rab 27a CRISPR/Cas9 KO Plasmid (h) - sc-401116 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a HDR Plasmid (h) - sc-401116-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a Double Nickase Plasmid (h) - sc-401116-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a Double Nickase Plasmid (h2) - sc-401116-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a CRISPR Activation Plasmid (h) - sc-401116-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a CRISPR Activation Plasmid (h2) - sc-401116-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a Lentiviral Activation Particles (h) - sc-401116-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a Lentiviral Activation Particles (h2) - sc-401116-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 27a siRNA (h) - sc-41834 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rab 27a shRNA Plasmid (h) - sc-41834-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rab 27a shRNA (h) Lentiviral Particles - sc-41834-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rab27a RNAi - H00005873-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Rab27a RNAi - H00005873-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Rab27a RNAi - H00005873-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU091501 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17825 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17825 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

RAB27A siRNA (Human) - CRH3963 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Rab27a RNAi - H00005873-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Rab27a RNAi - H00005873-R04 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

RAB27A - MBS829955 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human RAB27A (NM_183236.2) - SHH388100 from Creative biogene Category siRNA Species Reactivities Human

RAB27A shRNA Plasmid (Human) - CHH3963 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

RAB27A miRNA 3'UTR clone - MiUTR3H-06325 from Creative biogene Species Reactivities Human

RAB27A miRNA 3'UTR clone - MiUTR3H-06326 from Creative biogene Species Reactivities Human

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