RAB27A

Gene Symbol RAB27A
Entrez Gene 5873
Alt Symbol GS2, HsT18676, RAB27, RAM
Species Human
Gene Type protein-coding
Description RAB27A, member RAS oncogene family
Other Description GTP-binding protein Ram|rab-27|ras-related protein Rab-27A
Swissprots Q9Y5U3 O00195 Q6FI40 P51159 Q9UIR9
Accessions AAD47629 AAL39097 EAW77476 EAW77477 EAW77478 EAW77479 P51159 AF125393 AAD43049 AF498953 AAM21101 AK312836 BAG35690 AV661679 BC078139 BC107680 AAI07681 BC132800 AAI32801 BC136423 AAI36424 BM014705 CA398159 CA437806 CR457076 CAG33357 CR536496 CAG38735 CR541693 CAG46494 DA182503 DA553342 HQ258130 ADR82884 U38654 AAC50271 U57094 AAC51195 XM_005254576 XP_005254633 XM_011521852 XP_011520154 XM_011521853 XP_011520155 XM_011521854 XP_011520156 XM_011521855 XP_011520157 XM_011521856 XP_011520158 NM_004580 NP_004571 NM_183234 NP_899057 NM_183235 NP_899058 NM_183236 NP_899059
Function Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. {ECO:0000269|PubMed:18812475}.
Subcellular Location Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles.
Tissue Specificity Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells. {ECO:0000269|PubMed:15548590}.

Rab 27a (C-20) - sc-22990 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rab 27a (C-20): sc-22990. Western blot analysis of Rab 27a expression in non-transfected: sc-117752 (A) and mouse Rab 27a transfected: sc-122891 (B) 293T whole cell lysates.

Rab 27a (D-4) - sc-136996 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 27a (D-4): sc-136996. Western blot analysis of Rab 27a expression in non-transfected 293T: sc-117752 (A), mouse Rab 27a transfected 293T: sc-122891 (B), C32 (C) and SK-MEL-28 (D) whole cell lysates.

Rab 27a (E-4) - sc-136995 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 27a (E-4): sc-136995. Western blot analysis of Rab 27a expression in non-transfected: sc-117752 (A) and mouse Rab 27a transfected: sc-122892 (B) 293T whole cell lysates.

Rab 27a (E-8) - sc-74586 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 27a (E-8): sc-74586. Western blot analysis of Rab 27a expression in SK-MEL-28 whole cell lysate.

Rab 27a (H-60) - sc-22756 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rab27a (H-60): sc-22756. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization.

Rab 27a (N-20) - sc-22988 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rab 27a (N-20): sc-22988. Western blot analysis of Rab 27a expression in non-transfected: sc-117752 (A) and mouse Rab 27a transfected: sc-122891 (B) 293T whole cell lysates.

Rab 27a (E12A-1) - sc-81914 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Rab 27a (E12A-1): sc-81914. Western blot analysis of Rab 27a expression in HL-60 whole cell lysate.

Anti-RAB27A antibody - ab55667 from Abcam

Prices $398.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
RAB27A antibody (ab55667) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lymphoma. Heat induced antigen retrieval with Citrate buffer pH 6 has been performed prior to immunostaining.

Anti-RAB27A antibody - ab124325 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RAB27A antibody (ab124325) at 1/500 dilutionLane 1 : HEK293 cell lysate.Lane 2 : Human fetal skin lysate.

Anti-RAB27A antibody - ab98339 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RAB27A antibody (ab98339) at 1 µg/ml + Human fetal stomach lysate at 10 µg

Anti-RAB27A antibody [EPR3021] - ab108983 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3021
ab108983 staining RAB27A in Rhesus monkey fetal kidney cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with formaldehyde and blocked with 10% serum for 1 hour at 37°C. Samples were incubated with primary antibody (1/100 in 1% FCS/PBS) for 1 hour at 37°C. An Alexa Fluor®568-conjugated Goat anti-rabbit IgG polyclonal (1/1000) was used as the secondary antibody.See Abreview

Anti-RAB27A antibody [EPR3021] (Alexa Fluor® 488) - ab197900 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3021
ab197900 staining RAB27A in Hek293 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab197900 at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-RAB27A / RAB27 Antibody - LS-C194031 from LifeSpan Bioscience

Prices $905.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (C-Terminus) - LS-C107910 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RAB27A antibody LS-C107910 Western blot of Fetal Stomach lysate.

Anti-RAB27A / RAB27 Antibody (aa136-164, Biotin) - LS-C284925 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (aa136-164, AP) - LS-C284927 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (aa136-164, APC) - LS-C284926 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (aa1-215) - LS-C178906 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (aa136-164, FITC) - LS-C284928 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (aa136-164, PE) - LS-C284929 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (aa122-222, Azide-free) - LS-C328437 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RAB27A / RAB27 Antibody (aa136-164) - LS-C324473 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody - LS-C341380 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (aa136-164, Azide-free, HRP) - LS-C284932 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB27A / RAB27 Antibody (C-Terminus) - LS-C204245 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Western blot. Anti-Rab27 antibody at 1:500 dilution. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.
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