Gene Symbol | RAPGEF5 |
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Entrez Gene | 9771 |
Alt Symbol | GFR, MR-GEF, REPAC |
Species | Human |
Gene Type | protein-coding |
Description | Rap guanine nucleotide exchange factor (GEF) 5 |
Other Description | M-Ras-regulated GEF|M-Ras-regulated Rap GEF|guanine nucleotide exchange factor for Rap1|rap guanine nucleotide exchange factor 5|related to Epac |
Swissprots | Q92565 A4D140 Q8IXU5 |
Accessions | EAL24270 EAW93746 Q92565 AA732485 AA815190 AA890636 AK295859 BAG58663 AL833195 CAI46177 AW511225 BC039203 AAH39203 BF512545 BP349215 D87467 BAA13406 DN996625 W56891 XM_005249914 XP_005249971 XM_005249916 XP_005249973 XM_011515652 XP_011513954 NM_012294 NP_036426 |
Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation. {ECO:0000269|PubMed:10777494, ECO:0000269|PubMed:10934204}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Widely expressed with highest levels in brain. |
Top Pathways | Rap1 signaling pathway |
Repac (E-15) - sc-243963 from Santa Cruz Biotechnology
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Anti-RAPGEF5 antibody - ab88492 from Abcam
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Anti-RAPGEF5 antibody - ab96269 from Abcam
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Anti-RAPGEF5 antibody - ab130355 from Abcam
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Anti-RAPGEF5 antibody - ab138068 from Abcam
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Anti-RAPGEF5 antibody - ab68111 from Abcam
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Anti-RAPGEF5 antibody [EPR6882] - ab129008 from Abcam
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Anti-RAPGEF5 / GFR Antibody (aa417-466) IHC-plus⢠- LS-B11458 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (N-Terminus, clone EPR6882) IHC-plus™ - LS-B10218 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa529-555, AP) - LS-C284974 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa529-555, APC) - LS-C284975 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa529-555, Biotin) - LS-C284976 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa529-555, FITC) - LS-C284977 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa529-555, Azide-free, HRP) - LS-C284978 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa529-555, PE) - LS-C284979 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa476-521) - LS-C313915 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa528-555) - LS-C324527 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa1-179) - LS-C185498 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa431-480) - LS-C120296 from LifeSpan Bioscience
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Anti-RAPGEF5 / GFR Antibody (aa529-555) - LS-C162442 from LifeSpan Bioscience
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RAPGEF5 Antibody - NBP1-68636 from Novus Biologicals
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RAPGEF5 Antibody - H00009771-B01P from Novus Biologicals
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RAPGEF5 Antibody - NBP2-38835 from Novus Biologicals
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RAPGEF5 Antibody - NBP1-32220 from Novus Biologicals
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RAPGEF5 Antibody (2E4) - H00009771-M09 from Novus Biologicals
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