Gene Symbol | RAPGEF5 |
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Entrez Gene | 9771 |
Alt Symbol | GFR, MR-GEF, REPAC |
Species | Human |
Gene Type | protein-coding |
Description | Rap guanine nucleotide exchange factor (GEF) 5 |
Other Description | M-Ras-regulated GEF|M-Ras-regulated Rap GEF|guanine nucleotide exchange factor for Rap1|rap guanine nucleotide exchange factor 5|related to Epac |
Swissprots | Q92565 A4D140 Q8IXU5 |
Accessions | EAL24270 EAW93746 Q92565 AA732485 AA815190 AA890636 AK295859 BAG58663 AL833195 CAI46177 AW511225 BC039203 AAH39203 BF512545 BP349215 D87467 BAA13406 DN996625 W56891 XM_005249914 XP_005249971 XM_005249916 XP_005249973 XM_011515652 XP_011513954 NM_012294 NP_036426 |
Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation. {ECO:0000269|PubMed:10777494, ECO:0000269|PubMed:10934204}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Widely expressed with highest levels in brain. |
Top Pathways | Rap1 signaling pathway |
Rap guanine nucleotide exchange factor (GEF) 5, ELISA Kit - MBS9319520 from MyBioSource
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Human GFR ELISA Kit - abx574925 from Abbexa
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Human RAPGEF5 ELISA Kit - E032814 from Biobool
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