Gene Symbol | REV1 |
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Entrez Gene | 51455 |
Alt Symbol | REV1L |
Species | Human |
Gene Type | protein-coding |
Description | REV1, polymerase (DNA directed) |
Other Description | AIBP80|DNA repair protein REV1|REV1 homolog|REV1- like|alpha integrin-binding protein 80|rev1-like terminal deoxycytidyl transferase |
Swissprots | Q9C0J4 Q53SI7 O95941 Q9NUP2 Q9UBZ9 |
Accessions | AAW82434 AAY24314 EAX01860 EAX01861 EAX01862 EAX01863 Q9UBZ9 AB047646 BAB21441 AF151538 AAF06731 AF206019 AAF18986 AF357886 AAK43708 AJ131720 CAB38231 AK002087 BAA92079 AK025176 AK307719 BC037734 AAH37734 BC130411 AAI30412 BM683065 XM_011511336 XP_011509638 XM_011511337 XP_011509639 XM_011511338 XP_011509640 XM_011511339 XP_011509641 XM_011511340 XP_011509642 XM_011511341 XP_011509643 XR_427092 XR_922941 NM_001037872 NP_001032961 NM_016316 NP_057400 |
Function | Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. {ECO:0000269|PubMed:10536157, ECO:0000269|PubMed:10760286, ECO:0000269|PubMed:11278384, ECO:0000269|PubMed:11485998, ECO:0000269|PubMed:22266823}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10536157, ECO:0000269|PubMed:11278384, ECO:0000269|PubMed:11485998}. |
Top Pathways | Fanconi anemia pathway |
Human REV1 protein fragment - ab162562 from Abcam
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Human REV1 protein fragment - ab180340 from Abcam
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REV1 Antibody Blocking Peptide - LS-E25552 from LifeSpan Bioscience
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REV1 Partial Recombinant Protein - H00051455-Q01 from Novus Biologicals
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REV1 blocking peptide - GTX25088-PEP from GeneTex
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REV1 protein (His tag) - 80R-3801 from Fitzgerald
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Human REV1 Homolog Protein - abx068905 from Abbexa
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Human REV1 Homolog Protein - abx068903 from Abbexa
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Human REV1 Homolog Protein - abx068904 from Abbexa
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REV1 Peptide - AC21-0381-P from Abcore
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REV1 / REV1L (51-256, His-tag) - AR51488PU-N from Acris Antibodies
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REV1 / REV1L (51-256, His-tag) - AR51488PU-S from Acris Antibodies
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REV1 / REV1L - H00051455-Q01-10 from Acris Antibodies
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REV1 / REV1L - H00051455-Q01-25 from Acris Antibodies
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REV1 Homolog (REV1), Human - 20-9514 from ARP American Research Products
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REV1 Homolog (REV1), Human - 20-9515 from ARP American Research Products
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REV1 Homolog (REV1), Human - 20-9516 from ARP American Research Products
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REV1,51-256aa, Human, His tag, E.coli - 01-P2668 from ARP American Research Products
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REV1L Peptide - 46-281P from ProSci
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REV1 fusion protein - Ag11975 from Proteintech Group
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Recombinant Human REV1, His-tagged - REV1-175H from Creative Biomart
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Recombinant Human REV1, His-tagged - REV1-2257H from Creative Biomart
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Recombinant REV1 Homolog (REV1) - RPM132Hu01 from Uscn Life Science Inc.
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Recombinant REV1 Homolog (REV1) - RPM132Hu02 from Uscn Life Science Inc.
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Recombinant REV1 Homolog (REV1) - RPM132Hu03 from Uscn Life Science Inc.
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