PIK3R3

Gene Symbol	PIK3R3
Entrez Gene	8503
Alt Symbol	p55, p55-GAMMA, p55PIK
Species	Human
Gene Type	protein-coding
Description	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Other Description	PI3-kinase regulatory subunit gamma|PI3-kinase subunit p55-gamma|PI3K regulatory subunit gamma|phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma|phosphatidylinositol 3-kinase regulatory subunit gamma|phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|ptdIns-3-kinase regulatory subunit p55-gamma
Swissprots	Q5T4P1 O60482 B2R9C1 Q92569 Q5T4P2 D3DQ12
Accessions	EAX06943 EAX06944 EAX06945 EAX06946 EAX06947 Q92569 AF028785 AAC39696 AK302049 BAG63440 AK304713 BAG65477 AK313726 BAG36468 BC005381 AAH05381 BC021622 AAH21622 BC094768 BX507484 BX537388 CAD97630 CR749649 CAH18443 D88532 BAA13636 DB047431 DQ891789 ABM82715 DQ894971 ABM85897 EU832448 ACE87620 EU832531 ACE86933 U90907 Y13809 CAB52195 NM_001114172 NP_001107644 NM_001303427 NP_001290356 NM_001303428 NP_001290357 NM_001303429 NP_001290358 NM_003629 NP_003620
Function	Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Tissue Specificity	Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.
Top Pathways	Apoptosis, VEGF signaling pathway, Focal adhesion, Toll-like receptor signaling pathway, Jak-STAT signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PI 3-kinase p55γ CRISPR/Cas9 KO Plasmid (h) - sc-402964 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ HDR Plasmid (h) - sc-402964-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ Double Nickase Plasmid (h) - sc-402964-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ Double Nickase Plasmid (h2) - sc-402964-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ CRISPR Activation Plasmid (h) - sc-402964-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ CRISPR Activation Plasmid (h2) - sc-402964-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ Lentiviral Activation Particles (h) - sc-402964-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ Lentiviral Activation Particles (h2) - sc-402964-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PI 3-kinase p55γ siRNA (h) - sc-39124 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PI 3-kinase p55γ shRNA Plasmid (h) - sc-39124-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PI 3-kinase p55γ shRNA (h) Lentiviral Particles - sc-39124-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU123491 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1667 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1671 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1669 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1668 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1672 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1670 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN16812 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16812 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

PIK3R3 siRNA (Human) - CRH5577 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PIK3R3 RNAi - H00008503-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human PIK3R3 (NM_003629.3) - SHH375796 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PIK3R3(NM_003629.3) - SHR114792 from Creative biogene Category siRNA Species Reactivities Human

Human PIK3R3 siRNA - orb266079 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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