Gene Symbol | PIK3R3 |
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Entrez Gene | 8503 |
Alt Symbol | p55, p55-GAMMA, p55PIK |
Species | Human |
Gene Type | protein-coding |
Description | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
Other Description | PI3-kinase regulatory subunit gamma|PI3-kinase subunit p55-gamma|PI3K regulatory subunit gamma|phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma|phosphatidylinositol 3-kinase regulatory subunit gamma|phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|ptdIns-3-kinase regulatory subunit p55-gamma |
Swissprots | Q5T4P1 O60482 B2R9C1 Q92569 Q5T4P2 D3DQ12 |
Accessions | EAX06943 EAX06944 EAX06945 EAX06946 EAX06947 Q92569 AF028785 AAC39696 AK302049 BAG63440 AK304713 BAG65477 AK313726 BAG36468 BC005381 AAH05381 BC021622 AAH21622 BC094768 BX507484 BX537388 CAD97630 CR749649 CAH18443 D88532 BAA13636 DB047431 DQ891789 ABM82715 DQ894971 ABM85897 EU832448 ACE87620 EU832531 ACE86933 U90907 Y13809 CAB52195 NM_001114172 NP_001107644 NM_001303427 NP_001290356 NM_001303428 NP_001290357 NM_001303429 NP_001290358 NM_003629 NP_003620 |
Function | Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. |
Tissue Specificity | Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. |
Top Pathways | Apoptosis, VEGF signaling pathway, Focal adhesion, Toll-like receptor signaling pathway, Jak-STAT signaling pathway |
Phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199) Antibody - 4228 from Cell Signaling Technology
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PI3 Kinase p55 (D2B3) Rabbit mAb - 11889 from Cell Signaling Technology
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PI 3-kinase p55γ (E-9) - sc-376615 from Santa Cruz Biotechnology
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PI 3-kinase p55γ (N-13) - sc-48644 from Santa Cruz Biotechnology
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Anti-PI 3 Kinase p55 gamma antibody - ab76460 from Abcam
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Anti-PI 3 Kinase p55 gamma antibody [EPR18415] - ab186612 from Abcam
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Anti-PI 3 Kinase p85 gamma antibody - Carboxyterminal end - ab37825 from Abcam
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Anti-PIK3R3 / p85 Gamma Antibody - LS-C38242 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa251-378) - LS-C126132 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody - LS-C90210 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa324-353, AP) - LS-C266372 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa324-353, APC) - LS-C266375 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa324-353, Biotin) - LS-C266376 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa324-353, Azide-free, HRP) - LS-C266378 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa324-353, FITC) - LS-C266377 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa324-353, PE) - LS-C266379 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa324-353) - LS-C324065 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa201-250) - LS-C80063 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody - LS-C332696 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa175-224) - LS-C206160 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa192-427) - LS-C185915 from LifeSpan Bioscience
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Anti-PIK3R3 / p85 Gamma Antibody (aa316-346) - LS-C99851 from LifeSpan Bioscience
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PI 3-Kinase p55 gamma Antibody (668619) [Unconjugated] - MAB6638 from Novus Biologicals
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PI 3-Kinase p55 gamma Antibody - AF5734 from Novus Biologicals
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PIK3R3 Antibody - NBP1-32636 from Novus Biologicals
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