RBM22

Gene Symbol RBM22
Entrez Gene 55696
Alt Symbol Cwc2, ZC3H16, fSAP47
Species Human
Gene Type protein-coding
Description RNA binding motif protein 22
Other Description RNA-binding motif protein 22|functional spliceosome-associated protein 47|pre-mRNA-splicing factor RBM22|zinc finger CCCH domain-containing protein 16
Swissprots O95607 B4DLI9 A6NDM5 Q9NW64
Accessions EAW61710 EAW61711 EAW61712 Q9NW64 AK001152 BAA91521 AK096728 AK297019 BAG59551 AL136933 CAB66867 AM393639 CAL38515 BC003402 AAH03402 DA534416 N23415 NM_018047 NP_060517
Function Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. {ECO:0000269|PubMed:17045351, ECO:0000269|PubMed:21122810, ECO:0000269|PubMed:22246180}.
Subcellular Location Nucleus. Cytoplasm. Note=Mainly located in the nucleus. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol.
Top Pathways Spliceosome

RBM22 (D-14) - sc-132056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RBM22 (E-15) - sc-132057 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RBM22 (N-14) - sc-132058 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RBM22 (B-19) - sc-102074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
RBM22 (B-19): sc-102074. Western blot analysis of RBM22 expression in Jurkat whole cell lysate.

Anti-RBM22 antibody - ab124074 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RBM22 antibody (ab124074) at 1/100 dilution + Jurkat cell line lysate at 35 µg

Anti-RBM22 Antibody (aa251-300) - LS-C80382 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RBM22 Antibody (aa370-420) - LS-C286189 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse RBM22 by Western Blot. Samples: Whole cell lysate from 293T (15 and 50 ug), HeLa (50 ug), Jurkat (50 ug), and mouse NIH3T3 (50 ug) cells. Antibodies: Affinity purified rabbit anti-RBM22 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-RBM22 Antibody (aa175-225) - LS-C290572 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse RBM22 by Western Blot. Samples: Whole cell lysate from 293T (15 and 50 ug), HeLa (50 ug), Jurkat (50 ug), and mouse NIH3T3 (50 ug) cells. Antibodies: Affinity purified rabbit anti-RBM22 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-RBM22 Antibody (aa301-350) - LS-C30507 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RBM22 antibody LS-C30507 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.

Anti-RBM22 Antibody (aa165-193) - LS-C162492 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RBM22 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human spleen tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-RBM22 Antibody (aa165-193, APC) - LS-C239819 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM22 Antibody (aa165-193, Biotin) - LS-C239818 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM22 Antibody (aa165-193, FITC) - LS-C239820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM22 Antibody (aa165-193, PE) - LS-C239824 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM22 Antibody (aa165-193, Azide-free, HRP) - LS-C248627 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM22 Antibody (aa165-193, AP) - LS-C239817 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM22 Antibody (aa164-193) - LS-C324564 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

RBM22 Antibody - NBP1-85379 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RBM22 Antibody [NBP1-85379] - Lane 1: Marker [kDa] 230, 110, 82, 49, 32, 26, 18. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

RBM22 Antibody - NBP1-57327 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

RBM22 Antibody - NBP2-22276 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RBM22 Antibody [NBP2-22276] - Whole cell lysate from 293T (15 and 50 ug), HeLa (50 ug), Jurkat (50 ug), and mouse NIH3T3 (50 ug) cells. NBP2-22276 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

RBM22 Antibody - NBP2-22275 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RBM22 Antibody - NBP2-20104 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RBM22 Antibody [NBP2-20104] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 D: THP-1 10% SDS PAGE gel, diluted at 1:1000.

RBM22 Antibody - H00055696-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RBM22 Antibody [H00055696-B01] - analysis of RBM22 expression in transfected 293T cell line by RBM22 MaxPab polyclonal antibody (B01). Lane 1: RBM22 transfected lysate (46.20 KDa). Lane 2: Non-transfected lysate.

Anti-RBM22 (AB1) antibody produced in rabbit - AV40888 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HeLa (<B>Cat. No. AV40888</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type HeLa

Anti-RBM22 (AB2) antibody produced in rabbit - AV40889 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RBM22 (ab2): <B>Cat. No. AV40889</B>: Immunohistochemistry of RBM22 in Human Muscle tissue with RBM22 antibody at 4-8 μg/mL.
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