RBM22

Gene Symbol RBM22
Entrez Gene 55696
Alt Symbol Cwc2, ZC3H16, fSAP47
Species Human
Gene Type protein-coding
Description RNA binding motif protein 22
Other Description RNA-binding motif protein 22|functional spliceosome-associated protein 47|pre-mRNA-splicing factor RBM22|zinc finger CCCH domain-containing protein 16
Swissprots O95607 B4DLI9 A6NDM5 Q9NW64
Accessions EAW61710 EAW61711 EAW61712 Q9NW64 AK001152 BAA91521 AK096728 AK297019 BAG59551 AL136933 CAB66867 AM393639 CAL38515 BC003402 AAH03402 DA534416 N23415 NM_018047 NP_060517
Function Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. {ECO:0000269|PubMed:17045351, ECO:0000269|PubMed:21122810, ECO:0000269|PubMed:22246180}.
Subcellular Location Nucleus. Cytoplasm. Note=Mainly located in the nucleus. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol.
Top Pathways Spliceosome

RBM22 CRISPR/Cas9 KO Plasmid (h) - sc-407427 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 HDR Plasmid (h) - sc-407427-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 Double Nickase Plasmid (h) - sc-407427-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 Double Nickase Plasmid (h2) - sc-407427-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 CRISPR Activation Plasmid (h) - sc-407427-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 CRISPR Activation Plasmid (h2) - sc-407427-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 Lentiviral Activation Particles (h) - sc-407427-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 Lentiviral Activation Particles (h2) - sc-407427-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RBM22 siRNA (h) - sc-91911 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RBM22 shRNA Plasmid (h) - sc-91911-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RBM22 shRNA (h) Lentiviral Particles - sc-91911-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RBM22 RNAi - H00055696-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU145001 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN18033 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18033 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RBM22 siRNA (Human) - CRJ0840 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RBM22 - MBS8203143 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RBM22 (NM_018047.2) - SHH390624 from Creative biogene

Category siRNA
Species Reactivities Human

RBM22 shRNA Plasmid (Human) - CHJ0840 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RBM22 miRNA 3'UTR clone - MiUTR3H-12442 from Creative biogene

Species Reactivities Human
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