INMT

Gene Symbol	INMT
Entrez Gene	11185
Alt Symbol	TEMT
Species	Human
Gene Type	protein-coding
Description	indolethylamine N-methyltransferase
Other Description	amine N-methyltransferase|aromatic alkylamine N-methyltransferase|arylamine N-methyltransferase|indolamine N-methyltransferase|nicotine N-methyltransferase|thioether S-methyltransferase
Swissprots	B8ZZ69 Q9UBY4 Q9UHQ0 Q3KP49 Q9P1Y2 O95050
Accessions	AAD04723 AAF18306 BAA94451 EAL24447 O95050 AF128846 AAF18304 AF128847 AAF18305 AK309519 AK313832 BC033813 AAH33813 BC103712 AAI03713 BC106902 AAI06903 BC106903 AAI06904 DA920005 NM_001199219 NP_001186148 NM_006774 NP_006765
Function	Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2- methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. {ECO:0000250, ECO:0000269|PubMed:10552930}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain. {ECO:0000269|PubMed:10552930}.
Top Pathways	Selenocompound metabolism, Tryptophan metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human INMT protein fragment - ab127269 from Abcam Category Protein Source E. coli Species Human

INMT Antibody Blocking Peptide - LS-E7852 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

INMT Antibody Blocking Peptide - LS-E17609 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human INMT Protein - H00011185-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

INMT-Antibody-Center-Blocking-peptide - BP5476c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human INMT protein - orb244309 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

INMT Blocking Peptide - 33R-4392 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

INMT - H00011185-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

INMT - H00011185-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

INMT fusion protein - Ag16121 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

INMT fusion protein - Ag17077 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human INMT, GST-tagged - INMT-115H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Indolethylamine N-methyltransferase(INMT) - CSB-YP011723HU CSB-BP011723HU CSB-MP011723HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Indolethylamine N-methyltransferase - CSB-EP011723HU from Cusabio Category Protein Source E.coli Species Human

INMT - TP318678 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

INMT Peptide, Human - M34GP07653H from Creative Peptides Category Peptide Source Synthetic. Species Human

INMT Recombinant Protein (OPCA01664) - OPCA01664 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant Human Indolethylamine N-methyltransferase(INMT) - RPC20053 from Biomatik Category Protein Prices $106.00, $242.00, $380.00, $594.00, $945.00, $1,424.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Human Indolethylamine N-methyltransferase - AP70449 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

INMT Recombinant Protein Antigen - NBP2-57073PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Indolethylamine N-methyltransferase, Recombinant Protein - MBS9420366 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Indolethylamine N-methyltransferase, Recombinant Protein - MBS1011652 from MyBioSource Category Protein Prices $180.00, $490.00, $715.00, $950.00, $1,170.00, $1,170.00, $1,170.00, $1,400.00, $1,860.00, $1,860.00, $1,860.00, $2,760.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 500 µg (Yeast), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Indolethylamine N-methyltransferase (INMT), Recombinant Protein - MBS1439251 from MyBioSource Category Protein Prices $1,015.00, $1,015.00, $1,245.00, $1,245.00, $1,560.00, $1,560.00, $2,025.00, $2,025.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

Recombinant Human INMT Protein (1-263 aa), His-SUMO-tagged - INMT-584H from Creative Biomart Category Protein Source E. coli Species Human

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