INMT

Gene Symbol INMT
Entrez Gene 11185
Alt Symbol TEMT
Species Human
Gene Type protein-coding
Description indolethylamine N-methyltransferase
Other Description amine N-methyltransferase|aromatic alkylamine N-methyltransferase|arylamine N-methyltransferase|indolamine N-methyltransferase|nicotine N-methyltransferase|thioether S-methyltransferase
Swissprots B8ZZ69 Q9UBY4 Q9UHQ0 Q3KP49 Q9P1Y2 O95050
Accessions AAD04723 AAF18306 BAA94451 EAL24447 O95050 AF128846 AAF18304 AF128847 AAF18305 AK309519 AK313832 BC033813 AAH33813 BC103712 AAI03713 BC106902 AAI06903 BC106903 AAI06904 DA920005 NM_001199219 NP_001186148 NM_006774 NP_006765
Function Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2- methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. {ECO:0000250, ECO:0000269|PubMed:10552930}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain. {ECO:0000269|PubMed:10552930}.
Top Pathways Selenocompound metabolism, Tryptophan metabolism

INMT CRISPR/Cas9 KO Plasmid (h) - sc-411585 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT HDR Plasmid (h) - sc-411585-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT Double Nickase Plasmid (h) - sc-411585-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT Double Nickase Plasmid (h2) - sc-411585-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT CRISPR Activation Plasmid (h) - sc-411585-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT CRISPR Activation Plasmid (h2) - sc-411585-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT Lentiviral Activation Particles (h) - sc-411585-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT Lentiviral Activation Particles (h2) - sc-411585-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INMT siRNA (h) - sc-89715 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

INMT shRNA Plasmid (h) - sc-89715-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

INMT shRNA (h) Lentiviral Particles - sc-89715-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

INMT RNAi - H00011185-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU138831 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10681 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10681 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10410 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10410

INMT siRNA (Human) - CRH7665 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

INMT - MBS826939 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human INMT (NM_006774.4) - SHH319589 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human INMT(NM_006774.4) - SHL178172 from Creative biogene

Category siRNA
Species Reactivities Human

Human INMT siRNA - orb268167 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

INMT shRNA Plasmid (Human) - CHH7665 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

INMT miRNA 3'UTR clone - MiUTR1H-04952 from Creative biogene

Species Reactivities Human
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