Gene Symbol | POU2F2 |
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Entrez Gene | 5452 |
Alt Symbol | OCT2, OTF2, Oct-2 |
Species | Human |
Gene Type | protein-coding |
Description | POU class 2 homeobox 2 |
Other Description | OTF-2|POU domain, class 2, transcription factor 2|homeobox protein|lymphoid-restricted immunoglobulin octamer-binding protein NF-A2|octamer-binding protein 2|octamer-binding transcription factor 2 |
Swissprots | Q9BRS4 Q16648 P09086 Q7M4M8 |
Accessions | CAA56933 EAW57098 EAW57099 EAW57100 EAW57101 EAW57102 EAW57103 EAW57104 EAW57105 EAW57106 EAW57107 P09086 AA832036 BC006101 AAH06101 BF062323 BT007438 AAP36106 CB995118 M22596 AAA64232 M36542 AAA36732 M36653 AAA36389 M36718 AAA59978 M36772 AAA36392 X13809 CAA32039 X13810 CAA32040 X53468 CAA37562 X53469 CAA37565 XM_005259010 XP_005259067 XM_011527040 XP_011525342 XM_011527041 XP_011525343 XM_011527042 XP_011525344 XM_011527043 XP_011525345 XM_011527044 XP_011525346 NM_001207025 NP_001193954 NM_001207026 NP_001193955 NM_001247994 NP_001234923 NM_002698 NP_002689 |
Function | Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. {ECO:0000269|PubMed:1739980, ECO:0000269|PubMed:2328728, ECO:0000269|PubMed:2901913, ECO:0000269|PubMed:2904654}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus. |
Tissue Specificity | Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147. {ECO:0000269|PubMed:2904654, ECO:0000269|PubMed:3072196}. |
Human Oct-2 full length protein - ab152624 from Abcam
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POU2F2 / OCT2 Antibody Blocking Peptide - LS-E2749 from LifeSpan Bioscience
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POU2F2 / OCT2 Antibody Blocking Peptide - LS-E27356 from LifeSpan Bioscience
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POU2F2 / OCT2 Antibody Blocking Peptide - LS-E27357 from LifeSpan Bioscience
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Recombinant Human OCT2 Protein - H00005452-P01 from Novus Biologicals
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POU2F2-Antibody-N-term-Blocking-peptide - BP13842a from Abgent, a WuXi AppTec company
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FasL Blocking Peptide - 33R-10715 from Fitzgerald
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OTF2 Blocking Peptide - 33R-10812 from Fitzgerald
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Oct2 Peptide - AC21-2182-P from Abcore
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Oct2 Peptide - AC21-2183-P from Abcore
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POU2F2 / OCT2 - H00005452-P01 from Acris Antibodies
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POU2F2 fusion protein - Ag24540 from Proteintech Group
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POU2F2 fusion protein - ag0955 from Proteintech Group
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Recombinant Octamer Binding Transcription Factor 2 (OCT2) - RPB554Hu01 from Uscn Life Science Inc.
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Recombinant Octamer Binding Transcription Factor 2 (OCT2) - RPB554Ra01 from Uscn Life Science Inc.
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OCT2 Blocking Peptide - CBP1913 from Cohesion Biosciences
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Oct-2 (H3) Peptide - BS1261P from Bioworld Technology
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Recombinant Octamer Binding Transcription Factor 2 (OCT2) - RPB554Hu01 from Cloud-clone
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Recombinant Human POU domain, class 2, transcription factor 2(POU2F2) - CSB-YP018394HU CSB-EP018394HU CSB-BP018394HU CSB-MP018394HU from Cusabio
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Oct-2 Blocking Peptide - 3575BP-50 from Biovision
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POU2F2 Protein - abx164156 from Abbexa
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POU domain, class 2, transcription factor 2 (POU2F2), Recombinant Protein - MBS951879 from MyBioSource
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OCT-2, Peptide - MBS843867 from MyBioSource
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POU2F2/OCT2, Peptide - MBS427865 from MyBioSource
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POU2F2/OCT2, Peptide - MBS428420 from MyBioSource
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