POU2F2

Gene Symbol POU2F2
Entrez Gene 5452
Alt Symbol OCT2, OTF2, Oct-2
Species Human
Gene Type protein-coding
Description POU class 2 homeobox 2
Other Description OTF-2|POU domain, class 2, transcription factor 2|homeobox protein|lymphoid-restricted immunoglobulin octamer-binding protein NF-A2|octamer-binding protein 2|octamer-binding transcription factor 2
Swissprots Q9BRS4 Q16648 P09086 Q7M4M8
Accessions CAA56933 EAW57098 EAW57099 EAW57100 EAW57101 EAW57102 EAW57103 EAW57104 EAW57105 EAW57106 EAW57107 P09086 AA832036 BC006101 AAH06101 BF062323 BT007438 AAP36106 CB995118 M22596 AAA64232 M36542 AAA36732 M36653 AAA36389 M36718 AAA59978 M36772 AAA36392 X13809 CAA32039 X13810 CAA32040 X53468 CAA37562 X53469 CAA37565 XM_005259010 XP_005259067 XM_011527040 XP_011525342 XM_011527041 XP_011525343 XM_011527042 XP_011525344 XM_011527043 XP_011525345 XM_011527044 XP_011525346 NM_001207025 NP_001193954 NM_001207026 NP_001193955 NM_001247994 NP_001234923 NM_002698 NP_002689
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. {ECO:0000269|PubMed:1739980, ECO:0000269|PubMed:2328728, ECO:0000269|PubMed:2901913, ECO:0000269|PubMed:2904654}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus.
Tissue Specificity Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147. {ECO:0000269|PubMed:2904654, ECO:0000269|PubMed:3072196}.

Oct-2 CRISPR/Cas9 KO Plasmid (h) - sc-417876 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 HDR Plasmid (h) - sc-417876-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 Double Nickase Plasmid (h) - sc-417876-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 Double Nickase Plasmid (h2) - sc-417876-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 CRISPR Activation Plasmid (h) - sc-417876-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 CRISPR Activation Plasmid (h2) - sc-417876-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 Lentiviral Activation Particles (h) - sc-417876-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 Lentiviral Activation Particles (h2) - sc-417876-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oct-2 siRNA (h) - sc-36121 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Oct-2 shRNA Plasmid (h) - sc-36121-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Oct-2 shRNA (h) Lentiviral Particles - sc-36121-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU086851 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17175 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17175 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

POU2F2 siRNA (Human) - CRH3654 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

OCT2 RNAi - H00005452-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human POU2F2 (NM_002698.4) - SHH380040 from Creative biogene

Category siRNA
Species Reactivities Human

Human POU2F2 siRNA - orb264156 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

POU2F2 shRNA Plasmid (Human) - CHH3654 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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