AR

Gene Symbol AR
Entrez Gene 367
Alt Symbol AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Species Human
Gene Type protein-coding
Description androgen receptor
Other Description androgen nuclear receptor variant 2|dihydrotestosterone receptor|nuclear receptor subfamily 3 group C member 4
Swissprots A2RUN2 Q9UD95 P10275 B1AKD7
Accessions AAA51772 AAA51778 AAA51886 AAB21256 AAB21257 AAB60346 AAF04001 CAA55328 CCV20035 EAX05380 P10275 AF162704 AAD45921 AF321914 AAK09423 AF321915 AAK09424 AF321916 AAK09425 AF321917 AAK09426 AI352339 BC132975 AAI32976 FJ235916 ACN39559 FJ235917 ACN39560 FJ235918 ACN39561 FJ235919 ACN39562 FJ235920 ACN39563 GU208210 ACZ81436 HM055487 ADK91081 HQ692823 ADZ17334 KF720403 AHC70786 KF720404 AHC70787 KF720405 AHC70788 KJ534771 AHW56411 L29496 AAA51770 M20132 AAA51729 M20260 AAA51774 M21748 AAA51771 M23263 AAA51775 M34233 AAA51780 M73069 AAA51735 NM_000044 NP_000035 NM_001011645 NP_001011645
Function Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. {ECO:0000269|PubMed:14664718, ECO:0000269|PubMed:15563469, ECO:0000269|PubMed:17591767, ECO:0000269|PubMed:17911242, ECO:0000269|PubMed:18084323, ECO:0000269|PubMed:19345326, ECO:0000269|PubMed:20980437}.
Subcellular Location Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1.
Tissue Specificity Isoform 2 is mainly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15634333}.
Top Pathways Prostate cancer, Oocyte meiosis

Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 647 Conjugate) - 7397 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D6F11
Confocal immunofluorescent analysis of LNCaP (positive, left) and DU 145 (negative, right) cells using Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 647 Conjugate) (blue pseudocolor). Actin filaments were labeled with Alexa Fluor ® 488 phalloidin (green).

Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 488 Conjugate) - 7395 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D6F11
Confocal immunofluorescent analysis of LNCaP (left) and DU 145 (right) cells using Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 488 Conjugate) (green) and Hexokinase I (C35C4) Rabbit mAb (Alexa Fluor ® 647 Conjugate) #3540 (blue pseudocolor). Actin filaments were labeled with DY-554 phalloidin (red).

Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 594 Conjugate) - 8938 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D6F11
Confocal immunofluorescent analysis of LNCaP (positive, left) and DU 145 (negative, right) cells using Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 594 Conjugate) (red). Actin filaments were labeled with Alexa Fluor ® 488 phalloidin (green).

Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 555 Conjugate) - 8956 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D6F11
Confocal immunofluorescent analysis of LNCaP (positive, left) and DU 145 (negative, right) cells using Androgen Receptor (D6F11) XP ® Rabbit mAb (Alexa Fluor ® 555 Conjugate) (red). Actin filaments were labeled with Alexa Fluor ® 488 phalloidin (green).

Androgen Receptor (D6F11) XP ® Rabbit mAb (PE Conjugate) - 8428 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D6F11
Flow cytometric analysis of Jurkat (blue) and LNCaP (green) cells using Androgen Receptor (D6F11) XP ® Rabbit mAb (PE Conjugate).

Androgen Receptor (D6F11) XP ® Rabbit mAb - 5153 from Cell Signaling Technology

Prices $109.00, $282.00
Sizes 20 µl (2 western blots), 100 µl (20 western blots)
Host Rabbit
Clonality Monoclonal
Clone D6F11
Western blot analysis of extracts from LNCaP (AR+), MCF7 (AR+), PC-3 (AR-), and DU 145 (AR-) cells using Androgen Receptor (D6F11) XP ® Rabbit mAb (upper) and β-Actin Antibody #4967 (lower).

Androgen Receptor Antibody - 3202 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from LNCaP cells using Androgen Receptor Antibody.

AR (N-20) - sc-816 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of AR expression in AT-3 (A), T-47D (B), ZR-75-1 (C,F) and MCF7 (D) whole cell lysates and SK-BR-3 nuclear extract (E). Antibodies tested include AR (N-20): sc-816 (A-E) and AR (441): sc-7305 (F).

p-AR (E-6) - sc-377546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of AR phosphorylation in untreated (A) and lambda protein phosphatase (sc-200312A) treated (B) MOLT-4 nuclear extracts. Antibodies tested include p-AR (E-6): sc-377546.

AR (441) - sc-7305 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AR (441): sc-7305. Immunofluorescence staining of methanol-fixed T-47D cells (A) and immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue (B) showing nuclear localization.

AR (C-19) - sc-815 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AR (C-19): sc-815. Western blot analysis of AR expression in LNCaP whole cell lysate.

AR (H-280) - sc-13062 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AR (H-280): sc-13062. Western blot analysis of AR expression in rat prostate tissue extract.

AR (AN1-15) - sc-56824 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

AR (G-13) - sc-109500 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AR (G-13): sc-109500. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing cytoplasmic and nuclear staining of glandular cells.

AR (F39.4.1) - sc-52309 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl supernatant
Host Mouse
Clonality Monoclonal
AR (F39.4.1): sc-52309. Western blot analysis of AR expression in LNCaP whole cell lysate.

p-AR (Ser 213) - sc-135635 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of phosphorylated Androgen Receptor expression in DU 145 cell extracts. Blots were probed with p-AR (Ser 210): sc-135635 preincubated with cognate phosphorylated peptide (A) and p-AR (Ser 210): sc-135635 (B).

p-AR (156C135.2) - sc-52894 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

p-AR (4H24) - sc-71773 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Androgen Receptor (phospho S210) antibody - ab71948 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Androgen Receptor (phospho S210) antibody (ab71948) at 1/500 dilutionLane 1 : conditioned LNCaP whole cell lysate immunoprecipitated by 4 µg of ab71948 at 5mgLane 2 : conditioned LNCaP whole cell lysate immunoprecipitated by 4 µg of ab71948 at 5mg with immunization peptide

Anti-Androgen Receptor (phospho S213) antibody - ab131346 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Androgen Receptor (phospho S213) antibody (ab131346) at 1/500 dilutionLane 1 : DU145 cell extracts with immunizing peptideLane 2 : DU145 cell extracts

Anti-Androgen Receptor (phospho S213) antibody - ab47562 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab47562, at 1/50 dilution, staining Androgen Receptor in Human prostate carcinoma by Immunohistochemistry, paraffin-embedded tissue. Left panel: no peptide; right panel: blocking phosphopeptide.

Anti-Androgen Receptor (phospho S515) antibody - ab128250 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Androgen Receptor (phospho S650) antibody - ab47563 from Abcam

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab47563, at 1/50 dilution, staining Androgen Receptor in Human prostate carcinoma by Immunohistochemistry, paraffin-embedded tissue. Left panel: no peptide; right panel: 1ug/ul blocking phosphopeptide.

Anti-Androgen Receptor (phospho S650) antibody - ab194866 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue labeling Androgen Receptor (phospho S650) with ab194866 at 1/50 dilution.

Anti-Androgen Receptor (phospho S791) antibody - ab128232 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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