Gene Symbol | AR |
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Entrez Gene | 367 |
Alt Symbol | AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM |
Species | Human |
Gene Type | protein-coding |
Description | androgen receptor |
Other Description | androgen nuclear receptor variant 2|dihydrotestosterone receptor|nuclear receptor subfamily 3 group C member 4 |
Swissprots | A2RUN2 Q9UD95 P10275 B1AKD7 |
Accessions | AAA51772 AAA51778 AAA51886 AAB21256 AAB21257 AAB60346 AAF04001 CAA55328 CCV20035 EAX05380 P10275 AF162704 AAD45921 AF321914 AAK09423 AF321915 AAK09424 AF321916 AAK09425 AF321917 AAK09426 AI352339 BC132975 AAI32976 FJ235916 ACN39559 FJ235917 ACN39560 FJ235918 ACN39561 FJ235919 ACN39562 FJ235920 ACN39563 GU208210 ACZ81436 HM055487 ADK91081 HQ692823 ADZ17334 KF720403 AHC70786 KF720404 AHC70787 KF720405 AHC70788 KJ534771 AHW56411 L29496 AAA51770 M20132 AAA51729 M20260 AAA51774 M21748 AAA51771 M23263 AAA51775 M34233 AAA51780 M73069 AAA51735 NM_000044 NP_000035 NM_001011645 NP_001011645 |
Function | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. {ECO:0000269|PubMed:14664718, ECO:0000269|PubMed:15563469, ECO:0000269|PubMed:17591767, ECO:0000269|PubMed:17911242, ECO:0000269|PubMed:18084323, ECO:0000269|PubMed:19345326, ECO:0000269|PubMed:20980437}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1. |
Tissue Specificity | Isoform 2 is mainly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15634333}. |
Top Pathways | Prostate cancer, Oocyte meiosis |
PathScan ® Total Androgen Receptor Sandwich ELISA Kit - 12850 from Cell Signaling Technology
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Rat AR / Androgen Receptor ELISA Kit (Sandwich ELISA) - LS-F6438 from LifeSpan Bioscience
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Human AR / Androgen Receptor ELISA Kit (Sandwich ELISA) - LS-F4505 from LifeSpan Bioscience
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Mouse AR / Androgen Receptor ELISA Kit (Sandwich ELISA) - LS-F6268 from LifeSpan Bioscience
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Mouse/Human/Rat AR / Androgen Receptor ELISA Kit (DNA-Binding ELISA) - LS-F737 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-AR / Androgen Receptor (Tyr363) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1704 from LifeSpan Bioscience
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Human Phospho-AR / Androgen Receptor (Ser650) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1762 from LifeSpan Bioscience
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Human AR / Androgen Receptor ELISA Kit (Cell-Based ELISA) - LS-F1796 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-AR / Androgen Receptor (Ser650) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F855 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-AR / Androgen Receptor (Tyr363) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F856 from LifeSpan Bioscience
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Human Androgen Receptor ELISA Kit - abx150644 from Abbexa
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Human Androgen Receptor ELISA Kit - abx052585 from Abbexa
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Androgen Receptor, Human, ELISA Kit - E01A0636 from ARP American Research Products
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Androgen Receptor, AR, Human, ELISA Kit - E-EL-H0493 from ARP American Research Products
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Androgen Receptor, AR, Rabbit, ELISA Kit - E-EL-RB0246 from ARP American Research Products
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Androgen Receptor, AR, Chicken, ELISA Kit - E-EL-Ch0933 from ARP American Research Products
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Androgen Receptor, AR, Porcine, ELISA Kit - E-EL-P1644 from ARP American Research Products
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Androgen Receptor, AR, Monkey, ELISA Kit - E-EL-MK1821 from ARP American Research Products
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Androgen Receptor Colorimetric Cell-Based ELISA Kit - CB5040 from Assay Biotechnology
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Androgen Receptor (Phospho-Tyr363) Colorimetric Cell-Based ELISA Kit - CBP1777 from Assay Biotechnology
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Androgen Receptor (Phospho-Ser650) Colorimetric Cell-Based ELISA - CBP1868 from Assay Biotechnology
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Androgen Receptor (Phospho-Ser94) Colorimetric Cell-Based ELISA - CBP1869 from Assay Biotechnology
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TFact™ Androgen Receptor (Phospho-Ser650) DNA-Binding ELISA - TFE-7019 from Assay Biotechnology
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TFact™ Androgen Receptor (Phospho-Tyr363) DNA-Binding ELISA - TFE-7020 from Assay Biotechnology
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Androgen Receptor TFact™ DNA-Binding ELISA - TFE-7021 from Assay Biotechnology
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