| Gene Symbol |
MILR1
|
| Entrez Gene |
284021
|
| Alt Symbol |
Allergin-1, C17orf60, MCA-32, MCA32
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mast cell immunoglobulin-like receptor 1
|
| Other Description |
allergin-1|allergy inhibitory receptor 1|mast cell antigen 32|probable mast cell antigen 32 homolog
|
| Swissprots |
B7ZM50 B4DUS1 A1L458 B9EGN0 D6RUW6 D6RUW8 Q7Z6M3
|
| Accessions |
CAJ75916 CBY88425 Q7Z6M3 AB542950 BAJ08251 AB542951 BAJ08252 AB542952 BAJ08253 BC014523 BC018972 BC053534 AAH53534 BC130406 AAI30407 BC136594 AAI36595 BC144272 AAI44273 BE296352 CD687595 XM_005276872 XP_005276929 XM_005276874 XP_005276931 XM_005276875 XP_005276932 XM_005276876 XP_005276933 XM_005276877 XP_005276934 XM_005276878 XP_005276935 XM_011524627 XP_011522929 NM_001085423 NP_001078892 NM_001291316 NP_001278245 NM_001291317 NP_001278246
|
| Function |
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE- mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:20526344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20526344}.
|
| Tissue Specificity |
Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level). {ECO:0000269|PubMed:20526344}.
|