Gene Symbol | MILR1 |
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Entrez Gene | 284021 |
Alt Symbol | Allergin-1, C17orf60, MCA-32, MCA32 |
Species | Human |
Gene Type | protein-coding |
Description | mast cell immunoglobulin-like receptor 1 |
Other Description | allergin-1|allergy inhibitory receptor 1|mast cell antigen 32|probable mast cell antigen 32 homolog |
Swissprots | B7ZM50 B4DUS1 A1L458 B9EGN0 D6RUW6 D6RUW8 Q7Z6M3 |
Accessions | CAJ75916 CBY88425 Q7Z6M3 AB542950 BAJ08251 AB542951 BAJ08252 AB542952 BAJ08253 BC014523 BC018972 BC053534 AAH53534 BC130406 AAI30407 BC136594 AAI36595 BC144272 AAI44273 BE296352 CD687595 XM_005276872 XP_005276929 XM_005276874 XP_005276931 XM_005276875 XP_005276932 XM_005276876 XP_005276933 XM_005276877 XP_005276934 XM_005276878 XP_005276935 XM_011524627 XP_011522929 NM_001085423 NP_001078892 NM_001291316 NP_001278245 NM_001291317 NP_001278246 |
Function | Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE- mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:20526344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20526344}. |
Tissue Specificity | Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level). {ECO:0000269|PubMed:20526344}. |
C17orf60 (C-14) - sc-245443 from Santa Cruz Biotechnology
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C17orf60 (S-18) - sc-245441 from Santa Cruz Biotechnology
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Anti-Allergin 1 antibody - C-terminal - ab177744 from Abcam
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Anti-MCA32 Antibody (aa253-302) - LS-C170746 from LifeSpan Bioscience
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Allergin-1 Antibody (767727) - MAB7638 from Novus Biologicals
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Allergin-1 Antibody - AF7364 from Novus Biologicals
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Allergin-1 Antibody (767727) [Alexa Fluor (R) 488] - FAB7638G from Novus Biologicals
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Allergin-1 Antibody (767727) [Allophycocyanin] - FAB7638A from Novus Biologicals
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Allergin-1 Antibody (767727) [PE] - FAB7638P from Novus Biologicals
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Allergin-1 Polyclonal Antibody - bs-7348R from Bioss
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Anti-C17orf60 antibody produced in rabbit - HPA014347 from Sigma-Aldrich
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MILR1 Antibody - C-terminal region (ARP69581_P050) - ARP69581_P050 from Aviva Systems Biology
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Anti -Allergin-1 (Allergy Inhibitory Receptor 1, C17orf60, MCA32, MCA32-1S2, MILR1) (PE) - 145386 from USBiological Life Science
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Anti -Allergin-1 (Allergy Inhibitory Receptor 1, C17orf60, MCA32, Mast Cell Antigen,MCA32-1S2, MILR1) (APC) - 145385 from USBiological Life Science
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Anti -Allergin-1 (Mast Cell Antigen, C17orf60, MCA32, MCA32-1S2, MILR1) - 145387 from USBiological Life Science
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Human Allergin-1 Antibody - AF7364 from R&D Systems
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Human Allergin-1 Affinity Purified Polyclonal Ab, Sheep IgG - AF7364-SP from R&D Systems
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Human Allergin-1 PE-conjugated Antibody - FAB7638P from R&D Systems
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Human Allergin-1 Alexa Fluor® 488-conjugated Antibody - FAB7638G from R&D Systems
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Human Allergin-1 APC-conjugated Antibody - FAB7638A from R&D Systems
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Human Allergin-1 Antibody - MAB7638 from R&D Systems
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Human Allergin-1 MAb (Clone 767727), Mouse IgG1 - MAB7638-SP from R&D Systems
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Anti-MILR1 (aa 253-302) polyclonal antibody - DPABH-12523 from Creative Diagnostics
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Allergin-1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-7348R-A350 from Bioss
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Allergin-1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-7348R-A488 from Bioss
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