Gene Symbol | METAP1 |
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Entrez Gene | 23173 |
Alt Symbol | MAP1A, MetAP1A |
Species | Human |
Gene Type | protein-coding |
Description | methionyl aminopeptidase 1 |
Other Description | MAP 1|metAP 1|methionine aminopeptidase 1|peptidase M 1 |
Swissprots | B4E2E6 P53582 |
Accessions | EAX06082 EAX06083 P53582 AK304239 BAG65108 AK309465 BC030054 AAH30054 CR936632 CAI56775 D42084 BAA07679 DA178462 XM_005262868 XP_005262925 XM_011531777 XP_011530079 XM_011531778 XP_011530080 XM_011531779 XP_011530081 NM_015143 NP_055958 |
Function | Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle. {ECO:0000255|HAMAP- Rule:MF_03174, ECO:0000269|PubMed:16274222, ECO:0000269|PubMed:17114291}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03174}. |
MetAP-1 CRISPR/Cas9 KO Plasmid (h) - sc-407948 from Santa Cruz Biotechnology
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MetAP-1 HDR Plasmid (h) - sc-407948-HDR from Santa Cruz Biotechnology
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MetAP-1 Double Nickase Plasmid (h) - sc-407948-NIC from Santa Cruz Biotechnology
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MetAP-1 Double Nickase Plasmid (h2) - sc-407948-NIC-2 from Santa Cruz Biotechnology
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MetAP-1 CRISPR Activation Plasmid (h) - sc-407948-ACT from Santa Cruz Biotechnology
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MetAP-1 CRISPR Activation Plasmid (h2) - sc-407948-ACT-2 from Santa Cruz Biotechnology
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MetAP-1 Lentiviral Activation Particles (h) - sc-407948-LAC from Santa Cruz Biotechnology
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MetAP-1 Lentiviral Activation Particles (h2) - sc-407948-LAC-2 from Santa Cruz Biotechnology
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MetAP-1 siRNA (h) - sc-61022 from Santa Cruz Biotechnology
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MetAP-1 shRNA Plasmid (h) - sc-61022-SH from Santa Cruz Biotechnology
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MetAP-1 shRNA (h) Lentiviral Particles - sc-61022-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13216 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13216 from Sigma-Aldrich
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METAP1 siRNA (Human) - CRH8056 from Cohesion Biosciences
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shRNA set against Human METAP1 (NM_015143.2) - SHH340559 from Creative biogene
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shRNA set against Human METAP1(NM_015143.2) - SHH185267 from Creative biogene
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Human METAP1 siRNA - orb268558 from Biorbyt
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METAP1 shRNA Plasmid (Human) - CHH8056 from Cohesion Biosciences
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METAP1 miRNA 3'UTR clone - MiUTR1H-06214 from Creative biogene
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