Gene Symbol | METAP1 |
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Entrez Gene | 23173 |
Alt Symbol | MAP1A, MetAP1A |
Species | Human |
Gene Type | protein-coding |
Description | methionyl aminopeptidase 1 |
Other Description | MAP 1|metAP 1|methionine aminopeptidase 1|peptidase M 1 |
Swissprots | B4E2E6 P53582 |
Accessions | EAX06082 EAX06083 P53582 AK304239 BAG65108 AK309465 BC030054 AAH30054 CR936632 CAI56775 D42084 BAA07679 DA178462 XM_005262868 XP_005262925 XM_011531777 XP_011530079 XM_011531778 XP_011530080 XM_011531779 XP_011530081 NM_015143 NP_055958 |
Function | Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle. {ECO:0000255|HAMAP- Rule:MF_03174, ECO:0000269|PubMed:16274222, ECO:0000269|PubMed:17114291}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03174}. |
MetAP-1 (C-10) - sc-376779 from Santa Cruz Biotechnology
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MetAP-1 (C-14) - sc-49236 from Santa Cruz Biotechnology
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MetAP-1 (H-140) - sc-134731 from Santa Cruz Biotechnology
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MetAP-1 (N-19) - sc-49238 from Santa Cruz Biotechnology
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Anti-Methionyl Aminopeptidase 1 antibody - ab21741 from Abcam
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Anti-Methionyl Aminopeptidase 1 antibody - ab130492 from Abcam
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Anti-Methionyl Aminopeptidase 1 antibody [EPR15452(B)] - ab185540 from Abcam
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Anti-METAP1 Antibody (aa52-386) - LS-C37365 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa52-386) - LS-C37366 from LifeSpan Bioscience
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Anti-METAP1 Antibody (clone 248CT14.6.1, AP) - LS-C250315 from LifeSpan Bioscience
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Anti-METAP1 Antibody (clone 248CT14.6.1, APC) - LS-C250316 from LifeSpan Bioscience
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Anti-METAP1 Antibody (clone 248CT14.6.1, FITC) - LS-C250318 from LifeSpan Bioscience
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Anti-METAP1 Antibody (clone 248CT14.6.1, Biotin) - LS-C250317 from LifeSpan Bioscience
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Anti-METAP1 Antibody (clone 248CT14.6.1, PE) - LS-C250320 from LifeSpan Bioscience
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Anti-METAP1 Antibody (clone 248CT14.6.1, Azide-free, HRP) - LS-C250319 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa188-216, AP) - LS-C263049 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa188-216, FITC) - LS-C263051 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa188-216, APC) - LS-C263050 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa188-216, Azide-free, HRP) - LS-C263052 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa188-216, PE) - LS-C263054 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa71-120) - LS-C111615 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa188-216, Biotin) - LS-C263053 from LifeSpan Bioscience
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Anti-METAP1 Antibody (clone 248CT14.6.1) - LS-C319177 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa187-216) - LS-C322967 from LifeSpan Bioscience
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Anti-METAP1 Antibody (aa188-216) - LS-C158132 from LifeSpan Bioscience
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