HDAC6

Gene Symbol	HDAC6
Entrez Gene	10013
Alt Symbol	CPBHM, HD6, JM21, PPP1R90
Species	Human
Gene Type	protein-coding
Description	histone deacetylase 6
Other Description	protein phosphatase 1, regulatory subunit 90
Swissprots	Q96CY0 Q6NT75 O94975 Q9UBN7 Q7L3E5
Accessions	CAF04396 EAW50744 EAW50745 EAW50746 EAW50747 EAW50748 Q9UBN7 AB020708 BAA74924 AF132609 AAD29048 AF174499 AAF36540 AJ011972 CAA09893 AK001543 BAG50935 AK024083 BAG51263 AK095124 BAG52988 AK122954 BAG53817 AK127118 AK131286 BAG54760 AK295884 BAG58680 AK302926 BAG64088 AK303012 BAG64143 AK309058 AL137696 CAB70878 BC005872 AAH05872 BC011498 AAH11498 BC013219 BC013737 AAH13737 BC069243 AAH69243 BT006649 AAP35295 JF432329 ADZ15546 XM_005272564 XP_005272621 XM_005272565 XP_005272622 XM_005272566 XP_005272623 XM_005272568 XP_005272625 XM_006724525 XP_006724588 XR_246712 XR_949014 NM_006044 NP_006035
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. {ECO:0000250}.
Subcellular Location	Nucleus. Cytoplasm. Perikaryon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, axon {ECO:0000250}. Note=It is mainly cytoplasmic, where it is associated with microtubules.
Top Pathways	Viral carcinogenesis, Alcoholism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human HDAC6 full length protein - ab42632 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

HDAC6 peptide - ab41708 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human HDAC6 peptide - ab93301 from Abcam Category Peptide

HDAC6 Antibody Blocking Peptide - LS-E716 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HDAC6 Antibody Blocking Peptide - LS-E11299 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HDAC6 Antibody Blocking Peptide - LS-E10993 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HDAC6 Antibody Blocking Peptide - LS-E13943 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HDAC6 Protein - H00010013-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human HDAC6 Protein - H00010013-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HDAC6 Peptide - P0218 from Novus Biologicals Category Peptide Species Human

HDAC6-Antibody-C-term-Blocking-Peptide - BP1106a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HDAC6 Enzyme - orb198359 from Biorbyt Category Protein Prices $553.00 Sizes 50 μg Species Human

HDAC6 peptide - orb218306 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse

HDAC 6 Blocking Peptide - 33R-10521 from Fitzgerald Category Peptide Prices $295.00 Sizes 50 µg

HDAC6 Blocking Peptide - 33R-10831 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Histone Deacetylase 6 Blocking Peptide - abx063637 from Abbexa Category Peptide Species Human, Mouse, Rat, Rabbit

Human Histone Deacetylase 6 Protein - abx067129 from Abbexa Category Protein Source E.coli Species Human

HDAC6 - H00010013-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HDAC6 - H00010013-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HDAC6 - H00010013-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HDAC6 - H00010013-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HDAC6 control peptide - AP00275CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Histone Deacetylase 6 (HDAC6), Human - 20-9016 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

Histone Deacetylase 6 (HDAC6), Human - 20-9017 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

HDAC6 Peptide - 7901P from ProSci Category Peptide Species Human

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