BCL2

Gene Symbol	BCL2
Entrez Gene	596
Alt Symbol	Bcl-2, PPP1R50
Species	Human
Gene Type	protein-coding
Description	B-cell CLL/lymphoma 2
Other Description	apoptosis regulator Bcl-2|protein phosphatase 1, regulatory subunit 50
Swissprots	Q13842 Q16197 C9JHD5 P10416 P10415
Accessions	AAD14111 AAO26045 CAR95111 CAR95112 CCA94580 CDM22285 CDM22286 EAW63136 EAW63137 EAW63138 EAW63139 P10415 AF401211 AAL02169 AI401297 BC027258 AAH27258 DQ891470 ABM82396 DQ894654 ABM85580 EU287875 ABX60202 M13994 AAA51813 M13995 AAA51814 M14745 AAA35591 X06487 CAA29778 XM_011526135 XP_011524437 XR_935246 XR_935247 XR_935248 NM_000633 NP_000624 NM_000657 NP_000648
Function	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). {ECO:0000269|PubMed:18570871}.
Subcellular Location	Mitochondrion outer membrane {ECO:0000269|PubMed:2250705}; Single-pass membrane protein {ECO:0000269|PubMed:2250705}. Nucleus membrane {ECO:0000269|PubMed:2250705}; Single-pass membrane protein {ECO:0000269|PubMed:2250705}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:2250705}; Single-pass membrane protein {ECO:0000269|PubMed:2250705}.
Tissue Specificity	Expressed in a variety of tissues.
Top Pathways	Toxoplasmosis, Epstein-Barr virus infection, MicroRNAs in cancer, Adrenergic signaling in cardiomyocytes, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BCL2 gene - orb142027 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human BCL2 gene - orb90792 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone in cloning vector - HG10195-M from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, C-HA tag - HG10195-CY from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10195-ANG from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, C-His tag - HG10195-CH from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10195-NF from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10195-CF from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10195-NM from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, N-HA tag - HG10195-NY from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10195-CM from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10195-ACG from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10195-ACR from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10195-ANR from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid, N-His tag - HG10195-NH from Sino Biological Species Human

Human BCL2/Bcl-2 transcript variant alpha Gene ORF cDNA clone expression plasmid - HG10195-UT from Sino Biological Species Human

Bcl-2/BCL2 - CL01219H02 from Elabscience Species Human Accession NM_000657.2

Human Bcl-2 ORF clone(NM_000633.2) - CDCL182829 from Creative biogene Species Human

Human BCL2 ORF Clone(NM_000657.2) - CDCR337373 from Creative biogene Species Human

Human BCL2 cDNA Clone(NM_000633.2) - CDFH001714 from Creative biogene Species Human

Human BCL2 cDNA Clone(NM_000657.2) - CDFH001715 from Creative biogene Species Human

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