Gene Symbol | TRIM23 |
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Entrez Gene | 373 |
Alt Symbol | ARD1, ARFD1, RNF46 |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 23 |
Other Description | ADP-ribosylation factor domain protein 1, 64kDa|ADP-ribosylation factor domain-containing protein 1|ARF domain protein 1|E3 ubiquitin-protein ligase TRIM23|GTP-binding protein ARD-1|RING finger protein 46|tripartite motif protein TRIM23|tripartite motif-containing 23|tripartite motif-containing protein 23 |
Swissprots | P36406 Q9BZY4 Q9BZY5 |
Accessions | EAW51349 EAW51350 EAW51351 P36406 AF230397 AAG50176 AF230398 AAG50177 AF230399 AAG50178 AI679928 AK292814 BAF85503 BC022510 AAH22510 BI859501 DQ893646 ABM84572 DQ895584 ABM86510 L04510 AAA35940 XM_005248497 XP_005248554 NM_001656 NP_001647 NM_033227 NP_150230 NM_033228 NP_150231 |
Function | Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit. {ECO:0000269|PubMed:15684077}. |
Subcellular Location | Endomembrane system {ECO:0000269|PubMed:9671726}. Golgi apparatus membrane {ECO:0000269|PubMed:9671726}. Lysosome membrane {ECO:0000269|PubMed:9671726}. Note=Membrane-associated with the Golgi complex and lysosomal structures. |
Human TRIM23 full length protein - ab114830 from Abcam
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Human TRIM23 full length protein - ab152195 from Abcam
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Human TRIM23 protein fragment - ab152196 from Abcam
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TRIM23 Antibody Blocking Peptide - LS-E2583 from LifeSpan Bioscience
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TRIM23 Antibody Blocking Peptide - LS-E11480 from LifeSpan Bioscience
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TRIM23 Antibody Blocking Peptide - LS-E11180 from LifeSpan Bioscience
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TRIM23 Antibody Blocking Peptide - LS-E13653 from LifeSpan Bioscience
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Recombinant Human TRIM23 Protein - H00000373-P02 from Novus Biologicals
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TRIM23 Recombinant Protein - H00000373-P01 from Novus Biologicals
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Recombinant Human TRIM23 Protein - H00000373-Q01 from Novus Biologicals
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TRIM23-Antibody-N-term-Blocking-peptide - BP13641a from Abgent, a WuXi AppTec company
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NIPP1 blocking peptide - GTX25300-PEP from GeneTex
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TRIM23 blocking peptide - GTX89759-PEP from GeneTex
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TRIM23 Blocking Peptide - 33R-1761 from Fitzgerald
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TRIM23 Blocking Peptide - 33R-7981 from Fitzgerald
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TRIM23 Blocking Peptide - 33R-4421 from Fitzgerald
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ARD1 Blocking Peptide - abx063114 from Abbexa
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TRIM23 / ARD1 - H00000373-P01-10 from Acris Antibodies
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TRIM23 / ARD1 - H00000373-P01-25 from Acris Antibodies
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TRIM23 / ARD1 - H00000373-P02 from Acris Antibodies
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TRIM23 / ARD1 - H00000373-Q01-10 from Acris Antibodies
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TRIM23 / ARD1 - H00000373-Q01-25 from Acris Antibodies
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Ard1 fusion protein - ag11439 from Proteintech Group
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TRIM23 fusion protein - ag3302 from Proteintech Group
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NAA10 Enzyme - BP002805-ENZ-158 from Syd Labs
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