CLK1

Gene Symbol CLK1
Entrez Gene 1195
Alt Symbol CLK, CLK/STY, STY
Species Human
Gene Type protein-coding
Description CDC-like kinase 1
Other Description CDC28/CDC2-like kinase|dual specificity protein kinase CLK1|protein tyrosine kinase STY
Swissprots Q0P694 Q8N5V8 B4DFW7 P49759
Accessions AAY14722 CAV30732 EAW70215 EAW70216 EAW70217 EAW70218 EAW70219 P49759 AI251890 AK025306 AK289365 BAF82054 AK294295 BAG57578 AK307301 AK316127 BAH14498 BC028149 AAH28149 BC028573 BC031549 AAH31549 BE241788 DA225472 DB164846 L29219 AAA61480 L29222 AAB59459 M59287 NM_001162407 NP_001155879 NM_004071 NP_004062 NR_027855 NR_027856 NM_001024646
Function Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. {ECO:0000269|PubMed:10480872, ECO:0000269|PubMed:19168442}.
Subcellular Location Nucleus.
Tissue Specificity Endothelial cells. {ECO:0000269|PubMed:19168442}.
Top Pathways Legionellosis

CLK1 (K-13) - sc-47957 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLK1 (K-13): sc-47957. Western blot analysis of CLK1 expression in NIH/3T3 whole cell lysate.

CLK1 (N-17) - sc-47959 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLK1 (N-17): sc-47959. Western blot analysis of CLK1 expression in non-transfected: sc-117752 (A) and human CLK1 transfected: sc-113676 (B) 293T whole cell lysates.

CLK1 (C-14) - sc-47956 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CLK1/4 (K-19) - sc-47958 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLK1/4 (K-19): sc-47958. Western blot analysis of CLK1 expression in non-transfected sc-117750 (A) and human CLK1 transfected: sc-113676 (B) whole cell lysates and mouse pancreas tissue extract (C).

Anti-CLK1 antibody - ab74044 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CLK1 antibody (ab74044) at 1/500 dilutionLane 1 : Extracts from 293 cellsLane 2 : Extracts from 293 cells with immunizing peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-CLK1 antibody - ab66994 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CLK1 antibody (ab66994) at 1/500 dilutionLane 1 : CLK1 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.

Anti-CLK1 antibody - ab151429 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CLK1 antibody (ab151429) at 1/1000 dilution + Hep G2 whole cell lysate at 30 µg

Anti-CLK1 antibody - N-terminal - ab71408 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CLK1 antibody - N-terminal (ab71408) at 1/100 dilution + Y79 cell line lysate at 12.5 µg

Anti-CLK1 / CLK Antibody (aa52-80, AP) - LS-C255035 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (aa52-80, Biotin) - LS-C255037 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (aa52-80, APC) - LS-C255036 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (aa52-80, FITC) - LS-C255038 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (aa52-80, Azide-free, HRP) - LS-C255039 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (aa52-80, PE) - LS-C255040 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (N-Terminus, AP) - LS-C276342 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (aa35-84) - LS-C135263 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CLK1 antibody LS-C135263 Western blot of 293T cell lysate.

Anti-CLK1 / CLK Antibody (N-Terminus, FITC) - LS-C276345 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (N-Terminus, Biotin) - LS-C276344 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (N-Terminus, APC) - LS-C276343 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (N-Terminus, Azide-free, HRP) - LS-C276346 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody - LS-C306994 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (aa52-80) - LS-C320446 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (N-Terminus, PE) - LS-C276347 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK1 / CLK Antibody (N-Terminus) - LS-C99886 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-hCLK1-C84 antibody in Y79 cell line lysate. hCLK1-C84(arrow) was detected using the purified antibody.

Anti-CLK1 / CLK Antibody (N-Terminus) - LS-C330380 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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