CLK1

Gene Symbol	CLK1
Entrez Gene	1195
Alt Symbol	CLK, CLK/STY, STY
Species	Human
Gene Type	protein-coding
Description	CDC-like kinase 1
Other Description	CDC28/CDC2-like kinase|dual specificity protein kinase CLK1|protein tyrosine kinase STY
Swissprots	Q0P694 Q8N5V8 B4DFW7 P49759
Accessions	AAY14722 CAV30732 EAW70215 EAW70216 EAW70217 EAW70218 EAW70219 P49759 AI251890 AK025306 AK289365 BAF82054 AK294295 BAG57578 AK307301 AK316127 BAH14498 BC028149 AAH28149 BC028573 BC031549 AAH31549 BE241788 DA225472 DB164846 L29219 AAA61480 L29222 AAB59459 M59287 NM_001162407 NP_001155879 NM_004071 NP_004062 NR_027855 NR_027856 NM_001024646
Function	Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. {ECO:0000269|PubMed:10480872, ECO:0000269|PubMed:19168442}.
Subcellular Location	Nucleus.
Tissue Specificity	Endothelial cells. {ECO:0000269|PubMed:19168442}.
Top Pathways	Legionellosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CLK1 full length protein - ab114706 from Abcam Category Protein Source Wheat germ Species Human

Human CLK1 protein fragment - ab152284 from Abcam Category Protein Source Wheat germ Species Human

CLK1-Antibody-N-term-Blocking-Peptide - BP7529a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLK1 - H00001195-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CLK1 - H00001195-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CLK1 - H00001195-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CLK1 - H00001195-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CLK1 - H00001195-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CLK1 - P4669 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

CLK1 - P5693 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

CLK1 fusion protein - ag14552 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CLK1 fusion protein - ag14214 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CDC-like Kinase 1, GST-tagged, Active - CLK1-284H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus .

Recombinant Human CDC-like Kinase 1, GST-tagged - CLK1-676H from Creative Biomart Category Protein Source E. coli .

Recombinant Human CLK1 - CLK1-27274TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human CLK1 - CLK1-567H from Creative Biomart Category Protein Source Mammalian Cells Species Human

CLK1, active - 14-920 from EMD Millipore Prices $318.00 Sizes 10 µg also available in 250μg size as catalog # 14-920m and in bulk as catalog # 14-920-k. Source N-terminal 6His-tagged, recombinant, human CLK1, amino acids 130-end expressed by baculovirus in Sf21 insect cells

CLK1, active - 14-920M from EMD Millipore Prices $2,544.00 Sizes 250 µg also available in 10μg size as catalog # 14-920 and in bulk as catalog # 14-920-k. Source N-terminal 6His-tagged, recombinant, human CLK1, amino acids 130-end expressed by baculovirus in Sf21 insect cells

CLK1 Blocking Peptide - CBP3858 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

CLK1 (R126) Peptide - BS2556P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Dual specificity protein kinase CLK1(CLK1) - CSB-YP005557HU CSB-EP005557HU CSB-BP005557HU CSB-MP005557HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human CLK1(aa 129-484) GST Active - CSI10282 from Cell Science Prices $615.00 Sizes 10 μg Species Human

Recombinant Human CLK1 Active GST-His - CRC047 from Cell Science Prices $1,795.00 Sizes 50 µg Source Baculovirus infected Sf9 cells Species Human

CLK1, active - 14-920-K from EMD Millipore Source N-terminal 6His-tagged, recombinant, human CLK1, amino acids 130-end expressed by baculovirus in Sf21 insect cells

Dual specificity protein kinase CLK1 (CLK1), Recombinant Protein - MBS952457 from MyBioSource Category Protein Prices $1,270.00, $1,270.00, $1,490.00, $1,490.00, $2,075.00, $2,075.00, $2,540.00, $2,540.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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