NHP2

Gene Symbol	NHP2
Entrez Gene	55651
Alt Symbol	DKCB2, NHP2P, NOLA2
Species	Human
Gene Type	protein-coding
Description	NHP2 ribonucleoprotein
Other Description	H/ACA ribonucleoprotein complex subunit 2|NHP2 ribonucleoprotein homolog|NHP2-like protein|nucleolar protein family A, member 2 (H/ACA small nucleolar RNPs)|snoRNP protein NHP2
Swissprots	Q9NX24 A6NKY8 Q9P095
Accessions	EAW53848 Q9NX24 AF161404 AAF28964 AF401217 AAL02173 AF401219 AAL02175 AJ293309 CAC08452 AK000486 BAA91198 BC000009 AAH00009 BC006387 AAH06387 BE797477 BG827491 BM913344 CR457238 CAG33519 NM_001034833 NP_001030005 NM_017838 NP_060308
Function	Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. {ECO:0000269|PubMed:15044956}.
Subcellular Location	Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Tissue Specificity	Expressed in brain, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus. Also expressed at lower levels in the liver. {ECO:0000269|PubMed:12020816}.
Top Pathways	Ribosome biogenesis in eukaryotes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NHP2 full length protein - ab102027 from Abcam Category Protein Source E. coli Species Human

Human NHP2 full length protein - ab185384 from Abcam Category Protein Source E. coli Species Human

NHP2 Recombinant Protein - H00055651-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NHP2 Partial Recombinant Protein - H00055651-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NHP2 Protein - NBP1-50949 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 100 µg, 500 µg Source E. coli Species Human

NHP2-Antibody-Center-Blocking-Peptide - BP17785c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NHP2 Protein (OPPA00158) - OPPA00158 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human NOLA2 protein - orb180362 from Biorbyt Category Protein Prices $306.00, $451.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source E.coli Species Human

Human NHP2 protein - orb168926 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source E. coli Species Human

NHP2 protein (His tag) - 80R-1624 from Fitzgerald Category Protein Prices $340.00 Sizes 100 µg Source E.coli

NOLA2 (1-153, His-tag) - AR09805PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 500 µg Source E. coli Species Human

NOLA2 (1-153, His-tag) - AR09805PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 100 µg Source E. coli Species Human

NOLA2 - H00055651-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NOLA2 - H00055651-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NOLA2 - H00055651-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NOLA2 - H00055651-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NHP2 Ribonucleoprotein Homolog, Human Recombinant - 228-12787-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human NHP2 Ribonucleoprotein Homolog - 228-12787-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human NHP2 Ribonucleoprotein Homolog - 228-12787-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

NHP2, 1-153aa, Human, His tag, E.coli - 01-NHP2 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Species Human

NHP2 fusion protein - Ag7580 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NHP2 fusion protein - Ag7251 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NHP2, 1-153aa, Recombinant Protein - GWB-P1173C from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 100 μg, 500 μg Source E.coli Species Human

NHP2 Human Protein - GWB-BSP552 from Genway Biotech Category Protein Prices $75.00, $165.00, $4,035.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human NHP2 Ribonucleoprotein Homolog (Yeast), His-tagged - NHP2-3399H from Creative Biomart Category Protein Source E.coli.

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