| Gene Symbol |
LTBR
|
| Entrez Gene |
4055
|
| Alt Symbol |
CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lymphotoxin beta receptor (TNFR superfamily, member 3)
|
| Other Description |
lymphotoxin B receptor|tumor necrosis factor C receptor|tumor necrosis factor receptor 2-related protein|tumor necrosis factor receptor superfamily member 3|tumor necrosis factor receptor type III
|
| Swissprots |
D3DUR2 P36941 B7Z1D2 F5GXE7
|
| Accessions |
BAD01488 CCA94576 EAW88801 EAW88802 P36941 AK027080 AK095418 BAG53051 AK128019 AK293187 BAH11468 BC026262 AAH26262 BX648074 DA679291 DC424721 DQ891995 ABM82921 DQ895185 ABM86111 L04270 AAA36757 L04489 XM_005253688 XP_005253745 XM_006718983 XP_006719046 NM_001270987 NP_001257916 NM_002342 NP_002333
|
| Function |
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. {ECO:0000269|PubMed:10799510, ECO:0000269|PubMed:8171323}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, HTLV-I infection, Viral carcinogenesis
|
![Western Blot: LTBR Overexpression Lysate (Adult Normal) [NBL1-12740] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LTBR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3398_LTBR%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12740-img0002.jpg)