Gene Symbol | LTBR |
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Entrez Gene | 4055 |
Alt Symbol | CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3 |
Species | Human |
Gene Type | protein-coding |
Description | lymphotoxin beta receptor (TNFR superfamily, member 3) |
Other Description | lymphotoxin B receptor|tumor necrosis factor C receptor|tumor necrosis factor receptor 2-related protein|tumor necrosis factor receptor superfamily member 3|tumor necrosis factor receptor type III |
Swissprots | D3DUR2 P36941 B7Z1D2 F5GXE7 |
Accessions | BAD01488 CCA94576 EAW88801 EAW88802 P36941 AK027080 AK095418 BAG53051 AK128019 AK293187 BAH11468 BC026262 AAH26262 BX648074 DA679291 DC424721 DQ891995 ABM82921 DQ895185 ABM86111 L04270 AAA36757 L04489 XM_005253688 XP_005253745 XM_006718983 XP_006719046 NM_001270987 NP_001257916 NM_002342 NP_002333 |
Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. {ECO:0000269|PubMed:10799510, ECO:0000269|PubMed:8171323}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, HTLV-I infection, Viral carcinogenesis |
Active human LTBR protein fragment - ab157287 from Abcam
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Human LTBR full length protein - ab152507 from Abcam
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Human LTBR protein fragment - ab151373 from Abcam
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Human LTBR protein fragment - ab186983 from Abcam
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Mouse LTBR protein fragment - ab185858 from Abcam
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Mouse LTBR protein fragment - ab198752 from Abcam
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LTBR Antibody Blocking Peptide - LS-E3840 from LifeSpan Bioscience
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Lymphotoxin beta R/TNFRSF3 Recombinant Protein - H00004055-P01 from Novus Biologicals
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LTBR-Antibody-N-term-Blocking-Peptide - BP16019a from Abgent, a WuXi AppTec company
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Recombinant Human Lymphotoxin beta R (LTbR) Fc Chimera, CF - 629-LR-100 from R&D Systems
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Recombinant Human LT beta R/TNFRSF3 Fc Chimera (CHO), CF - 7538-LR-100 from R&D Systems
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Recombinant human Tumor necrosis factor receptor superfamily member 3 (OPCA00739) - OPCA00739 from Aviva Systems Biology
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Human LTBR protein - orb245360 from Biorbyt
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Human TNFRSF3 protein - orb49699 from Biorbyt
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Cynomolgus LTBR protein - orb139299 from Biorbyt
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Human TNFRSF3 (Fc) protein - orb180445 from Biorbyt
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LTBR protein (His tag) - 80R-3453 from Fitzgerald
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LTBR protein (His tag) - 80R-4032 from Fitzgerald
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Human LTbR Protein - abx067855 from Abbexa
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LTBR Blocking Peptide - abx062892 from Abbexa
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LTBR / TNFR3 (28-227, His-tag) - AR51717PU-N from Acris Antibodies
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LTBR / TNFR3 (28-227, His-tag) - AR51717PU-S from Acris Antibodies
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LTBR / TNFR3 - H00004055-P01-10 from Acris Antibodies
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LTBR / TNFR3 - H00004055-P01-25 from Acris Antibodies
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Lymphotoxin Beta Receptor (LTbR), Human - 20-6704 from ARP American Research Products
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