TBRG1

Gene Symbol TBRG1
Entrez Gene 84897
Alt Symbol NIAM, TB-5
Species Human
Gene Type protein-coding
Description transforming growth factor beta regulator 1
Other Description nuclear interactor of ARF and MDM2
Swissprots Q8TCS4 Q66ZJ6 Q8TEI4 Q53GJ5 Q3YBR2 Q69YS7 Q96SV0
Accessions CAE89317 EAW67589 EAW67590 Q3YBR2 AK027527 BAB55177 AK027766 AK057749 BAB71559 AK074140 BAB84966 AK074594 AK222936 BAD96656 AL713631 CAD28450 AL831881 CAH10595 AY696294 AAU10523 BC018452 AAH18452 BC032312 AAH32312 BC041043 AAH41043 BC064392 BC073160 AAH73160 BC107428 BC109269 AAI09270 DA292015 DQ144542 AAZ76016 XM_005271709 XP_005271766 XM_005271711 XP_005271768 XM_011543040 XP_011541342 XR_428983 NM_032811 NP_116200 NR_016021
Function Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. {ECO:0000269|PubMed:17110379}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17110379}.
Tissue Specificity Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma. {ECO:0000269|PubMed:17110379}.

TBRG1 CRISPR/Cas9 KO Plasmid (h) - sc-413721 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 HDR Plasmid (h) - sc-413721-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 Double Nickase Plasmid (h) - sc-413721-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 Double Nickase Plasmid (h2) - sc-413721-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 CRISPR Activation Plasmid (h) - sc-413721-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 CRISPR Activation Plasmid (h2) - sc-413721-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 Lentiviral Activation Particles (h) - sc-413721-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 Lentiviral Activation Particles (h2) - sc-413721-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBRG1 siRNA (h) - sc-96858 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TBRG1 shRNA Plasmid (h) - sc-96858-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TBRG1 shRNA (h) Lentiviral Particles - sc-96858-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TBRG1 RNAi - H00084897-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU007171 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21101 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21101 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10866 from Sigma-Aldrich

Category miRNA

TBRG1 siRNA (Human) - CRJ3675 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TBRG1 - MBS8205949 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TBRG1 (NM_032811.2) - SHH424312 from Creative biogene

Category siRNA
Species Reactivities Human

Human TBRG1 siRNA - orb274176 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TBRG1 shRNA Plasmid (Human) - CHJ3675 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TBRG1 miRNA 3'UTR clone - MiUTR4H-TG08822 from Creative biogene

Species Reactivities Human
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