Gene Symbol | PRKD3 |
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Entrez Gene | 23683 |
Alt Symbol | EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU |
Species | Human |
Gene Type | protein-coding |
Description | protein kinase D3 |
Other Description | protein kinase C nu type|protein kinase EPK2|serine/threonine-protein kinase D3 |
Swissprots | Q53TR7 D6W587 Q8NEL8 O94806 |
Accessions | AAY14817 EAX00398 EAX00399 O94806 AA631772 AB015982 BAA36514 AI865038 AK027585 BAG51354 AK122883 AW515068 BC012820 BC030706 AAH30706 BI262400 BQ051077 BU173084 JF432526 ADZ15743 Z25429 CAA80916 XM_005264237 XP_005264294 XM_005264238 XP_005264295 XM_006711978 XP_006712041 XM_011532732 XP_011531034 NM_005813 NP_005804 |
Function | Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18076381}. Membrane {ECO:0000269|PubMed:18076381}. Note=Translocation to the cell membrane is required for kinase activation. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Rap1 signaling pathway |
PKD3/PKCν (D57E6) Rabbit mAb - 5655 from Cell Signaling Technology
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PKC ν (C-15) - sc-33409 from Santa Cruz Biotechnology
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PKC ν (L-20) - sc-33408 from Santa Cruz Biotechnology
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PKC ν (N-20) - sc-33407 from Santa Cruz Biotechnology
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PKC ν (Q-24) - sc-130846 from Santa Cruz Biotechnology
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Anti-PKC nu antibody - ab203188 from Abcam
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Anti-PKC nu antibody - ab140921 from Abcam
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Anti-PKC nu antibody - ab5286 from Abcam
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Anti-PKC nu antibody - ab5285 from Abcam
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Anti-PKC nu antibody - ab70392 from Abcam
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Anti-PKC nu antibody - ab57012 from Abcam
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Anti-PKD3 / PRKD3 Antibody (C-Terminus) - LS-C91531 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (clone 11C1061) - LS-C184099 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody - LS-C189176 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa361-390, AP) - LS-C223661 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa361-390, APC) - LS-C223662 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa361-390, Biotin) - LS-C223663 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa361-390, FITC) - LS-C223664 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa361-390, Azide-free, HRP) - LS-C223665 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa361-390, PE) - LS-C223668 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa220-249, APC) - LS-C223756 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa220-249, Biotin) - LS-C223758 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody - LS-C62233 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa220-249, AP) - LS-C223757 from LifeSpan Bioscience
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Anti-PKD3 / PRKD3 Antibody (aa220-249, FITC) - LS-C223759 from LifeSpan Bioscience
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