Gene Symbol | PRKD3 |
---|---|
Entrez Gene | 23683 |
Alt Symbol | EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU |
Species | Human |
Gene Type | protein-coding |
Description | protein kinase D3 |
Other Description | protein kinase C nu type|protein kinase EPK2|serine/threonine-protein kinase D3 |
Swissprots | Q53TR7 D6W587 Q8NEL8 O94806 |
Accessions | AAY14817 EAX00398 EAX00399 O94806 AA631772 AB015982 BAA36514 AI865038 AK027585 BAG51354 AK122883 AW515068 BC012820 BC030706 AAH30706 BI262400 BQ051077 BU173084 JF432526 ADZ15743 Z25429 CAA80916 XM_005264237 XP_005264294 XM_005264238 XP_005264295 XM_006711978 XP_006712041 XM_011532732 XP_011531034 NM_005813 NP_005804 |
Function | Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18076381}. Membrane {ECO:0000269|PubMed:18076381}. Note=Translocation to the cell membrane is required for kinase activation. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Rap1 signaling pathway |
PKC ν siRNA (h) - sc-44789 from Santa Cruz Biotechnology
|
||||||||
PKC ν shRNA Plasmid (h) - sc-44789-SH from Santa Cruz Biotechnology
|
||||||||
PKC ν shRNA (h) Lentiviral Particles - sc-44789-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU029961 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1855 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1854 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1856 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN2310 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2310 from Sigma-Aldrich
|
||||||||
PRKD3 siRNA (Human) - CRH8437 from Cohesion Biosciences
|
||||||||
PRKD3/nPKC nu RNAi - H00023683-R04 from Novus Biologicals
|
||||||||
shRNA set against Human PRKD3 (NM_005813.3) - SHH382936 from Creative biogene
|
||||||||
PRKD3 shRNA Plasmid (Human) - CHH8437 from Cohesion Biosciences
|
||||||||
PRKD3 miRNA 3'UTR clone - MiUTR1H-08286 from Creative biogene
|