| Gene Symbol |
PRKD3
|
| Entrez Gene |
23683
|
| Alt Symbol |
EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein kinase D3
|
| Other Description |
protein kinase C nu type|protein kinase EPK2|serine/threonine-protein kinase D3
|
| Swissprots |
Q53TR7 D6W587 Q8NEL8 O94806
|
| Accessions |
AAY14817 EAX00398 EAX00399 O94806 AA631772 AB015982 BAA36514 AI865038 AK027585 BAG51354 AK122883 AW515068 BC012820 BC030706 AAH30706 BI262400 BQ051077 BU173084 JF432526 ADZ15743 Z25429 CAA80916 XM_005264237 XP_005264294 XM_005264238 XP_005264295 XM_006711978 XP_006712041 XM_011532732 XP_011531034 NM_005813 NP_005804
|
| Function |
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18076381}. Membrane {ECO:0000269|PubMed:18076381}. Note=Translocation to the cell membrane is required for kinase activation.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Rap1 signaling pathway
|