YWHAQ

Gene Symbol	YWHAQ
Entrez Gene	10971
Alt Symbol	14-3-3, 1C5, HS1
Species	Human
Gene Type	protein-coding
Description	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
Other Description	14-3-3 protein T-cell|14-3-3 protein tau|14-3-3 protein theta|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Swissprots	Q9UP48 D6W4Z5 P27348 Q5TZU8 Q567U5
Accessions	AAX93143 AAY24326 CAJ42708 EAX00977 EAX00978 EAX00979 P27348 AA729400 AF070556 AAC28640 AK297624 BAG60000 AK302208 BAG63566 AK309462 AK316158 BAH14529 AM393330 CAL38208 AM393338 CAL38216 AM393358 CAL38236 AM393674 CAL38550 BC001197 BC050601 AAH50601 BC056867 AAH56867 BC093019 AAH93019 BT020014 AAV38817 HY044745 X56468 CAA39840 X57347 CAA40622 NM_006826 NP_006817
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. {ECO:0000269|PubMed:12177059}.
Subcellular Location	Cytoplasm. Note=In neurons, axonally transported to the nerve terminals.
Tissue Specificity	Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. {ECO:0000269|PubMed:11080204}.
Top Pathways	Cell cycle, Pathogenic Escherichia coli infection, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human YWHAQ gene - orb91314 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-YWHAQ-cDNA-Clone - DC08057 from Abgent, a WuXi AppTec company Prices $330.75 Sizes 10 µg Species Human Accession BC056867

YWHAQ cDNA (ANA11435) - ANA11435 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC050601

YWHAQ - MBS1269256 from MyBioSource Species Human Accession BC056867

Human YWHAQ cDNA clone(NM_006826.2) - CDFH021437 from Creative Biomart Species Human Accession NM_006826.2

Human YWHAQ cDNA clone(NM_006826.2) - CDFH021438 from Creative Biomart Species Human Accession NM_006826.2

Human YWHAQ ORF clone(NM_006826.2) - CDCL186806 from Creative Biomart Species Human Accession NM_006826.2

Human YWHAQ ORF Clone(NM_006826.2) - CDCR293757 from Creative Biomart Species Human Accession NM_006826.2

Human YWHAQ ORF Clone(NM_006826.2) - CDCR293758 from Creative Biomart Species Human Accession NM_006826.2

Human YWHAQ ORF Clone(NM_006826.2) - CDCR293759 from Creative Biomart Species Human Accession NM_006826.2

Human YWHAQ ORF Clone(NM_006826.2) - CDCL181550 from Creative Biomart Species Human Accession NM_006826.2

human YWHAQ ORF clone - CDCH102200 from Creative Biomart Species Human Accession NM_006826

human YWHAQ ORF clone - CDCH102201 from Creative Biomart Species Human Accession NM_006826

Human YWHAQ Gene ORF cDNA clone in cloning vector - HG10845-M from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, N-HA tag - HG10845-NY from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10845-M-F from Sino Biological Species Human

Human YWHAQ Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10845-M-N from Sino Biological Species Human Accession NM_006826.2

Human YWHAQ Gene ORF cDNA clone expression plasmid, C-His tag - HG10845-CH from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10845-ACR from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10845-ANR from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid - HG10845-UT from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10845-ACG from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10845-ANG from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10845-NF from Sino Biological Species Human

Human YWHAQ Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10845-NM from Sino Biological Species Human

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