YWHAQ

Gene Symbol	YWHAQ
Entrez Gene	10971
Alt Symbol	14-3-3, 1C5, HS1
Species	Human
Gene Type	protein-coding
Description	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
Other Description	14-3-3 protein T-cell|14-3-3 protein tau|14-3-3 protein theta|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Swissprots	Q9UP48 D6W4Z5 P27348 Q5TZU8 Q567U5
Accessions	AAX93143 AAY24326 CAJ42708 EAX00977 EAX00978 EAX00979 P27348 AA729400 AF070556 AAC28640 AK297624 BAG60000 AK302208 BAG63566 AK309462 AK316158 BAH14529 AM393330 CAL38208 AM393338 CAL38216 AM393358 CAL38236 AM393674 CAL38550 BC001197 BC050601 AAH50601 BC056867 AAH56867 BC093019 AAH93019 BT020014 AAV38817 HY044745 X56468 CAA39840 X57347 CAA40622 NM_006826 NP_006817
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. {ECO:0000269|PubMed:12177059}.
Subcellular Location	Cytoplasm. Note=In neurons, axonally transported to the nerve terminals.
Tissue Specificity	Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. {ECO:0000269|PubMed:11080204}.
Top Pathways	Cell cycle, Pathogenic Escherichia coli infection, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human 14-3-3 Tau full length protein - ab85270 from Abcam Category Protein Prices $188.00 Sizes 20 µg Source E. coli Species Human

Human 14-3-3 Tau full length protein - ab116444 from Abcam Category Protein Prices $402.00 Sizes 100 µg Source E. coli Species Human

Human 14-3-3 Tau full length protein - ab70352 from Abcam Category Protein Prices $277.00 Sizes 50 µg Source E. coli Species Human

Human 14-3-3 Tau full length protein - ab85978 from Abcam Category Protein Prices $188.00 Sizes 50 µg Source E. coli Species Human

YWHAQ / 14-3-3 Theta Antibody Blocking Peptide - LS-E26510 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human 14-3-3 tau/theta Protein - NBC1-18393 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Source E.coli Species Human

14-3-3 tau/theta Recombinant Protein - H00010971-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

YWHAQ-Antibody-Center-Blocking-Peptide - BP2929c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

YWHAQ-Antibody-N-term-Blocking-Peptide - BP2929a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

14-3-3 theta blocking peptide - GTX88929-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

YWHAQ Protein (OPPA01563) - OPPA01563 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human YWHAQ GST tag protein - orb84717 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source E. coli Species Human

14-3-3 beta protein - 30R-3008 from Fitzgerald Category Protein Prices $295.00 Sizes 500 µg Source E.coli

YWHAQ Blocking Peptide - 33R-8902 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

14-3-3 Tau Peptide - AC21-1347-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

14-3-3 protein theta (1-245) - AR09103PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 500 µg Source E. coli Species Human

14-3-3 protein theta (1-245) - AR09103PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 100 µg Source E. coli Species Human

14-3-3 protein theta - H00010971-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

14-3-3 protein theta - H00010971-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human 14-3-3 protein theta - 230-00576-10 from RayBiotech Category Protein Prices $110.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human 14-3-3 protein theta - 230-00576-50 from RayBiotech Category Protein Prices $224.00 Sizes 50 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human 14-3-3 protein theta - 230-00576-100 from RayBiotech Category Protein Prices $336.00 Sizes 100 µg Source Escherichia coli (E.coli) Species Human

Tyr-3/Trp- 5 Monooxygenase Activation Protein Theta, Human Recombinant - 228-11657-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human YWHAQ - 228-11657-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human YWHAQ - 228-11657-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

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