CHST6

Gene Symbol CHST6
Entrez Gene 4166
Alt Symbol MCDC1
Species Human
Gene Type protein-coding
Description carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
Other Description C-GlcNAc6ST|GST4-beta|N-acetylglucosamine 6-O-sulfotransferase 5|carbohydrate sulfotransferase 6|corneal N-acetylglucosamine 6-sulfotransferase|corneal N-acetylglucosamine-6-O-sulfotransferase|galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta|glcNAc6ST-5|gn6st-5|hCGn6ST
Swissprots Q9GZX3 D3DUK3
Accessions AAG26327 ADG26740 ADG26741 ADG26742 EAW95640 EAW95641 Q9GZX3 AF280086 AAG48244 BC036640 BC041645 BC074834 AAH74834 BC074883 AAH74883 XM_005255955 XP_005256012 XM_011523085 XP_011521387 NM_021615 NP_067628
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N- acetyllactosamine structures. {ECO:0000269|PubMed:11352640, ECO:0000269|PubMed:12218059}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea. {ECO:0000269|PubMed:11017086, ECO:0000269|PubMed:11181564, ECO:0000269|PubMed:11352640}.
Top Pathways Glycosaminoglycan biosynthesis - keratan sulfate

Human CHST6 protein fragment - ab158867 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158867 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CHST6 Antibody Blocking Peptide - LS-E1604 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CHST6 Antibody Blocking Peptide - LS-E17674 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CHST6 Antibody Blocking Peptide - LS-E17675 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Carbohydrate Sulfotransferase 6/CHST6 Protein - H00004166-Q01 from Novus Biologicals

Category Protein
Prices $250.00
Sizes 2 µg
Source Wheat Germ
Species Human

CHST6-Antibody-C-term-Blocking-peptide - BP12350b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human CHST6, CF - 5326-ST-020 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Ser27-Asn395, with an N-terminal 6-His tag

CHST6 Blocking Peptide - 33R-10046 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CHST6 Blocking Peptide - 33R-7529 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CHST6 Blocking Peptide - abx161356 from Abbexa

Category Peptide
Species Human, Mouse, Rat

CHST6 - H00004166-Q01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

CHST6 - H00004166-Q01-10 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Source in vitro transl.
Species Human

CHST6 - H00004166-Q01-25 from Acris Antibodies

Category Protein
Prices $520.00
Sizes 25 µg
Source in vitro transl.
Species Human

CHST6 fusion protein - ag13653 from Proteintech Group

Category Protein
Source E. coli-derived, T-HIS
Species Human

CHST6 fusion protein - Ag24288 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50
Source E. coli -derived, PET28a
Species Human

Recombinant Human CHST6, His-tagged - CHST6-738H from Creative Biomart

Category Protein
Source CHO Cells
Species Human

CHST6 Blocking Peptide - CBP3855 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat

Recombinant Human Carbohydrate sulfotransferase 6(CHST6) - CSB-YP884425HU CSB-EP884425HU CSB-BP884425HU CSB-MP884425HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human CHST6 Protein, CF - 5326-ST from R&D Systems

Category Protein
Prices $329.00
Sizes 20 µg
Source Chinese Hamster Ovary cell line, CHO-derived Ser27-Asn395, with an N-terminal 6-His tag Accession # NP_067628
Species Human

CHST6 (full length, N-term HIS tag) - TP760211 from Acris Antibodies

Category Protein
Prices $199.00
Sizes 50 µg
Source E. coli
Species Human
CHST6

Carbohydrate sulfotransferase 6 (CHST6), Recombinant Protein - MBS1423394 from MyBioSource

Category Protein
Prices $1,165.00, $1,165.00, $1,395.00, $1,395.00, $1,870.00, $1,870.00, $2,330.00, $2,330.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

CHST6 Peptide, Human - M34GP03155H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

CHST6 peptide - orb234730 from Biorbyt

Category Peptide
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