CHST6

Gene Symbol CHST6
Entrez Gene 4166
Alt Symbol MCDC1
Species Human
Gene Type protein-coding
Description carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
Other Description C-GlcNAc6ST|GST4-beta|N-acetylglucosamine 6-O-sulfotransferase 5|carbohydrate sulfotransferase 6|corneal N-acetylglucosamine 6-sulfotransferase|corneal N-acetylglucosamine-6-O-sulfotransferase|galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta|glcNAc6ST-5|gn6st-5|hCGn6ST
Swissprots Q9GZX3 D3DUK3
Accessions AAG26327 ADG26740 ADG26741 ADG26742 EAW95640 EAW95641 Q9GZX3 AF280086 AAG48244 BC036640 BC041645 BC074834 AAH74834 BC074883 AAH74883 XM_005255955 XP_005256012 XM_011523085 XP_011521387 NM_021615 NP_067628
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N- acetyllactosamine structures. {ECO:0000269|PubMed:11352640, ECO:0000269|PubMed:12218059}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea. {ECO:0000269|PubMed:11017086, ECO:0000269|PubMed:11181564, ECO:0000269|PubMed:11352640}.
Top Pathways Glycosaminoglycan biosynthesis - keratan sulfate

CHST5/6 (H-59) - sc-367153 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CHST5/6 (H-59): sc-367153. Western blot analysis of CHST5/6 expression in HT-29 (A) and PANC-1 (B) whole cell lysates.

CHST5/6 (K-15) - sc-68027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CHST5/6 (K-15): sc-68027. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells.

CHST5/6 (N-15) - sc-68028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CHST6 antibody - ab201106 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHST6 antibody (ab201106)Lane 1 : MCF7 whole cell lysateLane 2 : H9C2 whole cell lysateLane 3 : sp20 whole cell lysate

Anti-CHST6 antibody - ab154332 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CHST6 antibody (ab154332) at 1/1000 dilution + HeLa whole cell lysate. at 30 µg

Anti-CHST6 antibody - ab84555 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CHST6 antibody (ab84555) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CHST6 antibody - C-terminal - ab170753 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue, labeling CHST6 with ab170753 at 1/10 dilution, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CHST6 Antibody (aa303-333, AP) - LS-C254827 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 Antibody (aa303-333, APC) - LS-C254828 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 Antibody (aa303-333, Biotin) - LS-C254829 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 Antibody (aa303-333, Azide-free, HRP) - LS-C254831 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 Antibody (aa303-333, PE) - LS-C254832 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 Antibody (aa303-333) - LS-C320383 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 Antibody (aa303-333, FITC) - LS-C254830 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 Antibody (aa331-380) - LS-C119805 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using CHST6 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CHST6 Antibody (aa288-337) - LS-C111202 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CHST6 antibody LS-C111202 Western blot of Jurkat lysate.

Anti-CHST6 Antibody (C-Terminus) - LS-C102325 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CHST6 antibody LS-C102325 Western blot of 293T cell lysate.

Anti-CHST6 Antibody (aa303-333) - LS-C168764 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CHST6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CHST6 Antibody (aa202-395, clone 1D1) - LS-C336985 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D1
Western blot of extracts (35ug) from 9 different cell lines by using anti-CHST6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Carbohydrate Sulfotransferase 6/CHST6 Antibody - NBP1-57928 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Carbohydrate Sulfotransferase 6/CHST6 Antibody - NBP1-57927 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Carbohydrate Sulfotransferase 6/CHST6 Antibody [NBP1-57927] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

Carbohydrate Sulfotransferase 6/CHST6 Antibody - NBP1-32912 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST6 (ab1) antibody produced in rabbit - SAB2100428 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHST6 (ab1): <B>Cat. No.SAB2100428</B>: CHST6 in 293T cell lysate with CHST6 antibody at 1.0 μg/mL.

Anti-CHST6 (ab2) antibody produced in rabbit - SAB2100429 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHST6 (ab2): <B>Cat. No.SAB2100429</B>: CHST6 in Jurkat cell lysate with CHST6 antibody at 1.0 μg/mL.

Anti-CHST6, C-Terminal antibody produced in rabbit - SAB4501842 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-CHST6, C-Terminal: <B>Cat. No. SAB4501842</B>: Immunofluorescence of A549 cells using Anti-CHST6, C-Terminal antibody. Cells on the left were treated with the Anti-CHST6, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-CHST6, C-Terminal antibody and the synthesized immunogen peptide.
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