Gene Symbol | TAX1BP3 |
---|---|
Entrez Gene | 30851 |
Alt Symbol | TIP-1 |
Species | Human |
Gene Type | protein-coding |
Description | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
Other Description | Tax interaction protein 1|glutaminase-interacting protein 3|tax-interacting protein 1|tax1-binding protein 3 |
Swissprots | D3DTJ6 O14907 Q7LCQ4 B2RD53 |
Accessions | AAF43104 EAW90491 EAW90492 EAW90493 O14907 AF028823 AAB84248 AF234997 AAG44368 AF277318 AAK69111 AK001327 AK315408 BAG37800 BC023980 AAH23980 BM973411 CB129195 HQ447711 ADQ32196 U90913 NM_001204698 NP_001191627 NM_014604 NP_055419 |
Function | May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:16855024, ECO:0000269|PubMed:21139582}. |
Subcellular Location | Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins. |
Tissue Specificity | Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:16855024}. |
Human TAX1BP3 full length protein - ab115716 from Abcam
|
||||||||||
TAX1BP3 Recombinant Protein - H00030851-P01 from Novus Biologicals
|
||||||||||
Recombinant Human TAX1BP3 Protein - NBP1-72533 from Novus Biologicals
|
||||||||||
Human TAX1BP3 protein - orb245210 from Biorbyt
|
||||||||||
TAX1BP3 protein (His tag) - 80R-2036 from Fitzgerald
|
||||||||||
TAX1BP3 (1-124, His-tag) - AR50119PU-N from Acris Antibodies
|
||||||||||
TAX1BP3 (1-124, His-tag) - AR50119PU-S from Acris Antibodies
|
||||||||||
TAX1BP3 - H00030851-P01-10 from Acris Antibodies
|
||||||||||
TAX1BP3 - H00030851-P01-25 from Acris Antibodies
|
||||||||||
TAX1BP3, 1-124aa, Human, His tag E.coli - 01-P1294 from ARP American Research Products
|
||||||||||
TAX1BP3 fusion protein - Ag2306 from Proteintech Group
|
||||||||||
TAX1BP3 Human - PRPS-988 from NeoScientific
|
||||||||||
Recombinant Human TAX1BP3 Protein - BP002233-PRO-981 from Syd Labs
|
||||||||||
TAX1BP3, 1-124aa, Recombinant Protein - GWB-P0744C from Genway Biotech
|
||||||||||
Recombinant Human TAX1BP3, His-tagged - TAX1BP3-28609TH from Creative Biomart
|
||||||||||
Recombinant Human TAX1BP3, GST-tagged - TAX1BP3-3118H from Creative Biomart
|
||||||||||
Recombinant Human Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3, His-tagged - TAX1BP3-4742H from Creative Biomart
|
||||||||||
TAX1BP3 1-124aa - CMB-1127 from Reagent Proteins
|
||||||||||
Recombinant human Tax1-binding protein 3 protein - CSB-EP044454h CSB-BP044454h CSB-MP044454h from Cusabio
|
||||||||||
Recombinant Human Tax1-binding protein 3(TAX1BP3) - CSB-RP044454h from Cusabio
|
||||||||||
Recombinant Human Tax1-binding protein 3(TAX1BP3) - CSB-YP023180HU CSB-EP023180HU CSB-BP023180HU CSB-MP023180HU from Cusabio
|
||||||||||
TAX1BP3, 1-124aa, Human, His tag E.coli - ATGP1294 from ATGen
|
||||||||||
TAX1BP3 - TP304776 from Acris Antibodies
|
||||||||||
Tax1, Recombinant Protein - MBS145162 from MyBioSource
|
||||||||||
Tax1-binding protein 3, Recombinant Protein - MBS717133 from MyBioSource
|