TAX1BP3

Gene Symbol TAX1BP3
Entrez Gene 30851
Alt Symbol TIP-1
Species Human
Gene Type protein-coding
Description Tax1 (human T-cell leukemia virus type I) binding protein 3
Other Description Tax interaction protein 1|glutaminase-interacting protein 3|tax-interacting protein 1|tax1-binding protein 3
Swissprots D3DTJ6 O14907 Q7LCQ4 B2RD53
Accessions AAF43104 EAW90491 EAW90492 EAW90493 O14907 AF028823 AAB84248 AF234997 AAG44368 AF277318 AAK69111 AK001327 AK315408 BAG37800 BC023980 AAH23980 BM973411 CB129195 HQ447711 ADQ32196 U90913 NM_001204698 NP_001191627 NM_014604 NP_055419
Function May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:16855024, ECO:0000269|PubMed:21139582}.
Subcellular Location Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins.
Tissue Specificity Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:16855024}.

TIP-1 CRISPR/Cas9 KO Plasmid (h) - sc-409914 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 HDR Plasmid (h) - sc-409914-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 Double Nickase Plasmid (h) - sc-409914-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 Double Nickase Plasmid (h2) - sc-409914-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 CRISPR Activation Plasmid (h) - sc-409914-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 CRISPR Activation Plasmid (h2) - sc-409914-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 Lentiviral Activation Particles (h) - sc-409914-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 Lentiviral Activation Particles (h2) - sc-409914-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP-1 siRNA (h) - sc-94102 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIP-1 shRNA Plasmid (h) - sc-94102-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIP-1 shRNA (h) Lentiviral Particles - sc-94102-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TAX1BP3 RNAi - H00030851-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU227781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21043 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21043 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07267 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07267

TAX1BP3 siRNA (Human) - CRH9361 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TAX1BP3 - MBS828640 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TAX1BP3 (NM_014604.3) - SHH423672 from Creative biogene

Category siRNA
Species Reactivities Human

Human TAX1BP3 siRNA - orb269863 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TAX1BP3 shRNA Plasmid (Human) - CHH9361 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TAX1BP3 miRNA 3'UTR clone - MiUTR3H-15659 from Creative biogene

Species Reactivities Human
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