ITGA4

Gene Symbol	ITGA4
Entrez Gene	3676
Alt Symbol	CD49D, IA4
Species	Human
Gene Type	protein-coding
Description	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Other Description	269C wild type|CD49 antigen-like family member D|VLA-4 subunit alpha|antigen CD49D, alpha-4 subunit of VLA-4 receptor|integrin alpha 4|integrin alpha-4|integrin alpha-4 subunit|integrin alpha-IV|very late activation protein 4 receptor, alpha 4 subunit
Swissprots	D3DPG4 Q7Z4L6 P13612
Accessions	AAB25486 AGZ05039 AGZ05040 AGZ05041 AGZ05042 AGZ05043 AGZ05044 AGZ05045 AGZ05046 AGZ05047 AGZ05048 AGZ05049 AGZ05050 AGZ05051 AGZ05052 AGZ05053 AGZ05054 AGZ05055 AGZ05056 AGZ05057 AGZ05058 AGZ05059 AGZ05060 AGZ05061 AGZ05062 AGZ05063 AGZ05064 AGZ05065 AGZ05066 AGZ05067 AGZ05068 AGZ05069 AGZ05070 AGZ05071 AGZ05072 AGZ05073 AGZ05074 AGZ05075 AGZ05076 AGZ05077 AGZ05078 AGZ05079 AGZ05080 AGZ05081 AGZ05082 AGZ05083 AGZ05084 AGZ05085 AGZ05086 AGZ05087 AGZ05088 AGZ05089 AGZ05090 AGZ05091 AGZ05092 AGZ05093 AGZ05094 AGZ05095 AGZ05096 AGZ05097 AGZ05098 AGZ05099 AGZ05100 AGZ05101 AGZ05102 AGZ05103 AGZ05104 AGZ05105 AGZ05106 AGZ05107 AGZ05108 AGZ05109 AGZ05110 AGZ05111 AGZ05112 AGZ05113 AGZ05114 AGZ05115 AGZ05116 AGZ05117 AGZ05118 AGZ05119 AGZ05120 AGZ05121 AGZ05122 AGZ05123 EAX10985 EAX10986 EAX10987 P13612 AB208885 BAD92122 AJ504733 CAD43289 AJ508356 CAD48165 AJ510246 CAD53326 AJ510247 CAD53327 AJ510248 CAD53328 AJ510249 CAD53329 AK303220 BAG64307 AK303478 BAG64514 AK310610 AK311738 BC016671 AAH16671 BC055419 AAH55419 BC080190 AAH80190 BC146277 AAI46278 BC156712 AAI56713 L12002 AAB59613 X16983 CAA34852 NM_000885 NP_000876
Function	Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. {ECO:0000269|PubMed:19064666}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Hypertrophic cardiomyopathy (HCM), PI3K-Akt signaling pathway, Leishmaniasis, Intestinal immune network for IgA production, Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse ITGA4 / VLA-4 / CD49d ELISA Kit (Sandwich ELISA) - LS-F9459 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.071 ng/ml Range 0.156-10 ng/ml

Mouse ITGA4 / VLA-4 / CD49d ELISA Kit (Sandwich ELISA) - LS-F11846 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 0.156-10 ng/ml

Human ITGA4 / VLA-4 / CD49d ELISA Kit (Sandwich ELISA) - LS-F11845 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Integrin alpha-4 (ITGA4/CD49D), Human, ELISA Kit - CSB-E17545h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Integrin alpha-4, ITGA4, Human, ELISA Kit - E1511h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Integrin Alpha 4, ELISA Kit - MBS102439 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha 4, ELISA Kit - MBS055623 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha 4, ELISA Kit - MBS074605 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha 4, ELISA Kit - MBS094333 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha 4, ELISA Kit - MBS079779 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha 4, ELISA Kit - MBS056245 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha 4, ELISA Kit - MBS075999 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) , ELISA Kit - MBS918697 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human ITGA4/CD49D is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.312 ng/ml-20 ng/ml.

ELISA Kit for Integrin Alpha 4 (ITGa4) - SEB315Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.071ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Integrin alpha-4(ITGA4/CD49D)ELISA kit - CSB-E17545h from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

Human Integrin alpha-4 ELISA Kit - abx251080 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human Integrin alpha-4 (ITGA4/CD49D) ELISA Kit - EKC34166 from Biomatik Category ELISA Kit Prices $795.00, $3,021.00, $5,645.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Human Integrin alpha-4 ELISA Kit - EKE53943 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.078 ng/mL Range 0.156-10 ng/mL

ITGA4 - EKH3548 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

ITGA4 ELISA Kit (Human) : 96 Wells (OKEH01078) - OKEH01078 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.078 ng/mL Range 0.156 - 10 ng/mL

Human ITGA4 ELISA Kit - E020148 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human ITGA4/CD49D is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined

Human Integrin alpha-4 ELISA Kit - EK3660 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.078 ng/mL Range 0.156-10 ng/mL

anti-LPAM-1 / Integrin alpha 4 / CD49d antibody [PS/2] (PE) - ARG20809 from Arigo Biolaboratories Category ELISA Kit

anti-LPAM-1 / Integrin alpha 4 / CD49d antibody [PS/2] - ARG20806 from Arigo Biolaboratories Category ELISA Kit

anti-LPAM-1 / Integrin alpha 4 / CD49d antibody [PS/2] (azide free) - ARG20810 from Arigo Biolaboratories Category ELISA Kit

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