Gene Symbol | HTT |
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Entrez Gene | 3064 |
Alt Symbol | HD, IT15 |
Species | Human |
Gene Type | protein-coding |
Description | huntingtin |
Other Description | huntington disease protein |
Swissprots | Q9UQB7 P42858 |
Accessions | ACJ05038 ACJ05039 ACJ05040 ACJ05043 ACJ05044 ACJ05045 ACJ05046 ACJ05047 ACJ05048 ACJ05049 ACJ05050 ACJ05051 ACJ05052 ACJ05053 ACJ05054 ACJ05055 ACJ05056 ACJ05057 ACJ05058 ACJ05059 ACJ05060 ACJ05061 ACJ05062 ACJ05064 CAA89024 CAA89025 CAA89839 EAW82474 EAW82475 EAW82476 EAW82477 EAW82478 P42858 AB016794 BAA36753 AB209506 BAD92743 AK025918 AK290544 BAF83233 BC014028 BC172756 AAI72756 KJ535072 AHW56711 L12392 AAB38240 L20431 AAA52702 NM_002111 NP_002102 |
Function | May play a role in microtubule-mediated transport or vesicle function. |
Subcellular Location | Cytoplasm. Nucleus. Note=The mutant Huntingtin protein colocalizes with AKAP8L in the nuclear matrix of Huntington disease neurons. Shuttles between cytoplasm and nucleus in a Ran GTPase-independent manner. |
Tissue Specificity | Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation. {ECO:0000269|PubMed:16391387}. |
Top Pathways | Huntington's disease |
Human Huntingtin protein fragment - ab112300 from Abcam
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Recombinant Human Huntingtin Protein - H00003064-Q01 from Novus Biologicals
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Huntingtin Peptide - NBP1-96945 from Novus Biologicals
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Huntingtin [p Ser421] Peptide - NBP1-96946 from Novus Biologicals
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Huntingtin - H00003064-Q01-10 from Acris Antibodies
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Huntingtin - H00003064-Q01-25 from Acris Antibodies
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Huntingtin control peptide - R1553CP from Acris Antibodies
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Huntingtin control peptide - R1553NP from Acris Antibodies
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Recombinant Human HTT - HTT-28315TH from Creative Biomart
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Recombinant Huntingtin (HTT) - RPH922Hu01 from Uscn Life Science Inc.
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Recombinant Huntingtin (HTT) - RPH922Mu01 from Uscn Life Science Inc.
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Recombinant Huntingtin (HTT) - RPH922Mu02 from Uscn Life Science Inc.
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Recombinant Huntingtin (HTT) - RPH922Ra01 from Uscn Life Science Inc.
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Recombinant Huntingtin (HTT) - RPH922Hu01 from Cloud-clone
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Recombinant Human Huntingtin(HTT) ,partial - CSB-YP010905HU CSB-EP010905HU CSB-BP010905HU CSB-MP010905HU from Cusabio
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Huntingtin (2845-3144) - sc-4516 WB from Santa Cruz Biotechnology
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HTT Peptide - abx164857 from Abbexa
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Huntingtin Protein, Peptide - MBS658259 from MyBioSource
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Huntingtin Protein - NBP1-89710PEP from Novus Biologicals
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HTT Peptide, Human - M34GP07358H from Creative Peptides
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Huntingtin fusion protein - Ag25922 from Proteintech Group
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Huntingtin, Recombinant Protein - MBS2031404 from MyBioSource
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Huntingtin (HTT), partial, Recombinant Protein - MBS952720 from MyBioSource
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Recombinant Human HTT Protein, MYC/DDK-tagged - HTT-3829H from Creative Biomart
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