HTT

Gene Symbol HTT
Entrez Gene 3064
Alt Symbol HD, IT15
Species Human
Gene Type protein-coding
Description huntingtin
Other Description huntington disease protein
Swissprots Q9UQB7 P42858
Accessions ACJ05038 ACJ05039 ACJ05040 ACJ05043 ACJ05044 ACJ05045 ACJ05046 ACJ05047 ACJ05048 ACJ05049 ACJ05050 ACJ05051 ACJ05052 ACJ05053 ACJ05054 ACJ05055 ACJ05056 ACJ05057 ACJ05058 ACJ05059 ACJ05060 ACJ05061 ACJ05062 ACJ05064 CAA89024 CAA89025 CAA89839 EAW82474 EAW82475 EAW82476 EAW82477 EAW82478 P42858 AB016794 BAA36753 AB209506 BAD92743 AK025918 AK290544 BAF83233 BC014028 BC172756 AAI72756 KJ535072 AHW56711 L12392 AAB38240 L20431 AAA52702 NM_002111 NP_002102
Function May play a role in microtubule-mediated transport or vesicle function.
Subcellular Location Cytoplasm. Nucleus. Note=The mutant Huntingtin protein colocalizes with AKAP8L in the nuclear matrix of Huntington disease neurons. Shuttles between cytoplasm and nucleus in a Ran GTPase-independent manner.
Tissue Specificity Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation. {ECO:0000269|PubMed:16391387}.
Top Pathways Huntington's disease

Huntingtin CRISPR/Cas9 KO Plasmid (h) - sc-401441 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin HDR Plasmid (h) - sc-401441-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin Double Nickase Plasmid (h) - sc-401441-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin Double Nickase Plasmid (h2) - sc-401441-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin CRISPR Activation Plasmid (h) - sc-401441-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin CRISPR Activation Plasmid (h2) - sc-401441-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin Lentiviral Activation Particles (h) - sc-401441-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin Lentiviral Activation Particles (h2) - sc-401441-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin siRNA (h) - sc-35617 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Huntingtin shRNA Plasmid (h) - sc-35617-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Huntingtin shRNA (h) Lentiviral Particles - sc-35617-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Huntingtin RNAi - H00003064-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU005971 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10405 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10405 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HTT siRNA (Human) - CRH2085 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTT - MBS8217121 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Huntingtin CRISPR/Cas9 KO Plasmid (h2) - sc-401441-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Huntingtin HDR Plasmid (h2) - sc-401441-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human HTT (NM_002111.6) - SHH316085 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HD(NM_002111.6) - SHH116093 from Creative biogene

Category siRNA
Species Reactivities Human

HTT shRNA Plasmid (Human) - CHH2085 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HTT miRNA 3'UTR clone - MiUTR1H-04413 from Creative biogene

Species Reactivities Human
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