Gene Symbol | M6PR |
---|---|
Entrez Gene | 4074 |
Alt Symbol | CD-MPR, MPR 46, MPR-46, MPR46, SMPR |
Species | Human |
Gene Type | protein-coding |
Description | mannose-6-phosphate receptor (cation dependent) |
Other Description | 46-kDa mannose 6-phosphate receptor|CD Man-6-P receptor|Mr 46,000 Man6PR|cation-dependent mannose-6-phosphate receptor|small mannose 6-phosphate receptor |
Swissprots | D3DUV5 A8K528 P20645 |
Accessions | CAB94715 CAD48709 CAF06410 EAW88596 EAW88597 EAW88598 EAW88599 P20645 AA648974 AK057556 AK222792 BAD96512 AK291143 BAF83832 AK312689 BAG35569 BC017111 AAH17111 BC024206 AAH24206 BG750588 BM546062 BU166950 CR457412 CAG33693 DC341018 HQ447561 ADQ32047 M16985 AAA59542 XM_005253376 XP_005253433 XM_011520672 XP_011518974 NM_001207024 NP_001193953 NM_002355 NP_002346 |
Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
Subcellular Location | Lysosome membrane; Single-pass type I membrane protein. |
Top Pathways | Lysosome, Phagosome |
Human M6PR (cation dependent) protein fragment - ab80157 from Abcam
|
||||||||||
Human M6PR (cation dependent) protein fragment - ab180308 from Abcam
|
||||||||||
M6PR Antibody Blocking Peptide - LS-E7100 from LifeSpan Bioscience
|
||||||||||
M6PR Antibody Blocking Peptide - LS-E7101 from LifeSpan Bioscience
|
||||||||||
M6PR Antibody Blocking Peptide - LS-E26609 from LifeSpan Bioscience
|
||||||||||
CD-M6PR Partial Recombinant Protein - H00004074-Q01 from Novus Biologicals
|
||||||||||
M6PR-Antibody-C-term-Blocking-peptide - BP2792b from Abgent, a WuXi AppTec company
|
||||||||||
M6PR-Antibody-N-term-Blocking-Peptide - BP2792a from Abgent, a WuXi AppTec company
|
||||||||||
M6PR (cation dependent) blocking peptide - GTX88825-PEP from GeneTex
|
||||||||||
Recombinant human Cation-dependent mannose-6-phosphate receptor (OPCA00466) - OPCA00466 from Aviva Systems Biology
|
||||||||||
Human M6PR protein - orb245141 from Biorbyt
|
||||||||||
M6PR Blocking Peptide - 33R-8035 from Fitzgerald
|
||||||||||
M6PR protein (His tag) - 80R-3808 from Fitzgerald
|
||||||||||
Mannose 6 Phosphate Receptor Peptide - AC21-1445-P from Abcore
|
||||||||||
M6PR (27-185, His-tag) - AR51495PU-N from Acris Antibodies
|
||||||||||
M6PR (27-185, His-tag) - AR51495PU-S from Acris Antibodies
|
||||||||||
M6PR - H00004074-Q01-10 from Acris Antibodies
|
||||||||||
M6PR - H00004074-Q01-25 from Acris Antibodies
|
||||||||||
M6PR, 27-185aa, Human, His tag, E.coli - 01-P2675 from ARP American Research Products
|
||||||||||
M6PR Peptide - 45-851P from ProSci
|
||||||||||
M6PR fusion protein - Ag10267 from Proteintech Group
|
||||||||||
M6PR fusion protein - Ag10259 from Proteintech Group
|
||||||||||
Recombinant Human M6PR, His-tagged - M6PR-29239TH from Creative Biomart
|
||||||||||
Recombinant Human M6PR, His-tagged - M6PR-182H from Creative Biomart
|
||||||||||
Recombinant Mannose-6-Phosphate Receptor (M6PR) - RPH700Hu01 from Uscn Life Science Inc.
|