SATB2

Gene Symbol	SATB2
Entrez Gene	23314
Alt Symbol	GLSS
Species	Human
Gene Type	protein-coding
Description	SATB homeobox 2
Other Description	DNA-binding protein SATB2|SATB family member 2|special AT-rich sequence-binding protein 2
Swissprots	Q4V763 Q9UPW6 Q3ZB87 A8K5Z8
Accessions	CAC09123 EAW70180 EAW70181 Q9UPW6 AB028957 BAA82986 AB209376 BAD92613 AJ438951 AK025127 BAB15073 AK056638 BAG51771 AK291463 BAF84152 BC098136 AAH98136 BC099723 AAH99723 BC103492 AAI03493 BC103500 AAI03501 EU446695 ABZ92224 XM_005246396 XP_005246453 XM_006712372 XP_006712435 XM_011510840 XP_011509142 NM_001172509 NP_001165980 NM_001172517 NP_001165988 NM_015265 NP_056080
Function	Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper- layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. {ECO:0000269|PubMed:14701874}.
Subcellular Location	Nucleus matrix {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00374, ECO:0000269|PubMed:14701874}.
Tissue Specificity	High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus. {ECO:0000269|PubMed:14701874}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SATB2 full length protein - ab132405 from Abcam Category Protein Source Wheat germ Species Human

Human SATB2 protein fragment - ab153215 from Abcam Category Protein Source Wheat germ Species Human

Mouse SATB2 peptide - ab34906 from Abcam Category Peptide

SATB2 Antibody Blocking Peptide - LS-E4205 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SATB2 Antibody Blocking Peptide - LS-E30509 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SATB2 Antibody Blocking Peptide - LS-E30510 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human SATB2 Protein - H00023314-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

SATB2 Partial Recombinant Protein - H00023314-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SATB2 Blocking Peptide - NBP1-76913PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

SATB2 Blocking Peptide - NBP1-76912PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

SATB2-Antibody-Center-Blocking-Peptide - BP16464c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SATB2 - H00023314-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SATB2 - H00023314-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SATB2 - H00023314-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SATB2 - H00023314-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SATB2 Control Peptide - AP30760CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SATB2 Control Peptide - AP30761CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SATB2 Peptide - 4629P from ProSci Category Peptide Species Human

SATB2 Peptide - 4627P from ProSci Category Peptide Species Human

SATB2 fusion protein - ag15920 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SATB2 fusion protein - Ag17237 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human DNA-binding protein SATB2(SATB2) - CSB-YP892170HU CSB-EP892170HU CSB-BP892170HU CSB-MP892170HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SATB2 Recombinant Protein Antigen - NBP1-92365PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SATB2 Recombinant Protein Antigen - NBP1-83619PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SATB2 Peptide, Human - M34GP13799H from Creative Peptides Category Peptide Source Synthetic. Species Human

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