SATB2

Gene Symbol SATB2
Entrez Gene 23314
Alt Symbol GLSS
Species Human
Gene Type protein-coding
Description SATB homeobox 2
Other Description DNA-binding protein SATB2|SATB family member 2|special AT-rich sequence-binding protein 2
Swissprots Q4V763 Q9UPW6 Q3ZB87 A8K5Z8
Accessions CAC09123 EAW70180 EAW70181 Q9UPW6 AB028957 BAA82986 AB209376 BAD92613 AJ438951 AK025127 BAB15073 AK056638 BAG51771 AK291463 BAF84152 BC098136 AAH98136 BC099723 AAH99723 BC103492 AAI03493 BC103500 AAI03501 EU446695 ABZ92224 XM_005246396 XP_005246453 XM_006712372 XP_006712435 XM_011510840 XP_011509142 NM_001172509 NP_001165980 NM_001172517 NP_001165988 NM_015265 NP_056080
Function Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper- layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. {ECO:0000269|PubMed:14701874}.
Subcellular Location Nucleus matrix {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00374, ECO:0000269|PubMed:14701874}.
Tissue Specificity High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus. {ECO:0000269|PubMed:14701874}.

SATB2 (H-118) - sc-98677 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

SATB2 (K-20) - sc-79049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SATB2 (K-20): sc-79049. Western blot analysis of SATB2 expression in non-transfected: sc-117752 (A) and human SATB2 transfected: sc-369978 (B) 293T whole cell lysates.

SATB2 (N-16) - sc-79050 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SATB2 (N-16): sc-79050. Western blot analysis of SATB2 expression in C6 (A), HT-1080 (B), Jurkat (C) and K-562 (D) whole cell lysates.

SATB2 (SATBA4B10) - sc-81376 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
ZnT-9 (919C1a): sc-81118 Western Blot analysis of human recombinant ZnT-9 fusion protein.

Anti-SATB2 antibody - ab34735 from Abcam

Prices $400.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SATB2 antibody (ab34735) at 1 µg/ml + Brain (Mouse) Tissue Lysate - normal tissue, 0 days old (ab7188) at 10 µgSecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/15000 dilutionPerformed under reducing conditions.

Anti-SATB2 antibody - ab69995 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-SATB2 antibody (ab69995) at 2 µg/mlLane 2 : Anti-SATB2 antibody (ab69995) at 4 µg/mlLane 1 : Mouse brain tissue lysateLane 2 : Mouse brain tissue lysateLysates/proteins at 15 µg per lane.

Anti-SATB2 antibody - ab69998 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-SATB2 antibody (ab69998) at 2 µg/mlLane 2 : Anti-SATB2 antibody (ab69998) at 4 µg/mlLane 1 : A20 cell lysateLane 2 : A20 cell lysateLysates/proteins at 15 µg per lane.

Anti-SATB2 antibody - ab119118 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-SATB2 antibody (ab119118) at 2 µg/mlLane 2 : Anti-SATB2 antibody (ab119118) at 4 µg/mlLane 1 : A20 cell lysate Lane 2 : A20 cell lysate

Anti-SATB2 antibody [EPNCIR130A] - ab92446 from Abcam

Prices $99.00, $397.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPNCIR130A
Anti-SATB2 antibody [EPNCIR130A] (ab92446) at 1/1000 dilution (purified) + SW1353 cell lysate at 20 µgSecondaryPeroxidase conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-SATB2 antibody [EPNCIR130B] - ab133328 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPNCIR130B
All lanes : Anti-SATB2 antibody [EPNCIR130B] (ab133328) at 1/1000 dilutionLane 1 : HT-1080 cell lysateLane 2 : Saos-2 cell lysateLane 3 : Human fetal brain lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-SATB2 antibody [SATBA4B10] - ab51502 from Abcam

Prices $401.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone SATBA4B10
Anti-SATB2 antibody [SATBA4B10] (ab51502) at 1/100 dilution + NIH3T3 whole cell lysate at 25 µgSecondaryAnti Mouse IgG antibody at 1/2500 dilution

Anti-SATB2 Antibody (aa616-731) - LS-C75710 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-SATB2 Antibody (aa410-439, AP) - LS-C285224 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa410-439, APC) - LS-C285225 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa410-439, Biotin) - LS-C285226 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa410-439, FITC) - LS-C285227 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa410-439, Azide-free, HRP) - LS-C285228 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa410-439, PE) - LS-C285230 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa250-300) - LS-C288640 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa683-733) - LS-C288643 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (aa409-439) - LS-C324918 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SATB2 Antibody (clone SATBA4B10) - LS-C184274 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone SATBA4B10
Western blot of immunized recombinant protein using SATB2 antibody.

Anti-SATB2 Antibody (aa410-439) - LS-C162875 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SATB2 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The SATB2 antibody detected the SATB2 protein (arrow).

Anti-SATB2 Antibody (N-Terminus) - LS-C53311 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 50 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of SATB2 in human brain with SATB2 antibody at 5 ug/ml.

Anti-SATB2 Antibody (C-Terminus) IHC-plus™ - LS-B4981 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SATB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4981 concentration 5 ug/ml.
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