| Gene Symbol |
OR51E2
|
| Entrez Gene |
81285
|
| Alt Symbol |
OR51E3P, OR52A2, PSGR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
olfactory receptor, family 51, subfamily E, member 2
|
| Other Description |
HPRAJ|olfactory receptor 51E2|olfactory receptor OR11-16|olfactory receptor, family 51, subfamily E, member 3 pseudogene|olfactory receptor, family 52, subfamily A, member 2|prostate specific G-protein coupled receptor|prostate-specific G-protein coupled receptor
|
| Swissprots |
Q9H255 B2RA63 Q6IF94
|
| Accessions |
AAG40776 CAJ56785 DAA04766 EAW68829 EAW68831 Q9H255 AF369708 AAK38728 AK314051 BAG36760 AY033942 AAK57550 BC020768 AAH20768 DQ892702 ABM83628 DQ895946 ABM86872 NM_030774 NP_110401
|
| Function |
Probable G protein-coupled receptor that is activated by the short chain fatty acids (SCFA) acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure (PubMed:23401498). May also be activated by steroid hormones and regulate cell proliferation (PubMed:19389702). May also function as an olfactory receptor being activated by beta-ionone (PubMed:19389702). {ECO:0000269|PubMed:19389702, ECO:0000269|PubMed:23401498}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:23401498}; Multi-pass membrane protein {ECO:0000269|PubMed:23401498}.
|
| Tissue Specificity |
Mainly expressed in the prostate. Also expressed in spleen, liver, olfactory epithelium and medulla oblongata. {ECO:0000269|PubMed:11707321, ECO:0000269|PubMed:16491480}.
|
| Top Pathways |
Olfactory transduction
|
![Western Blot: PSGR Overexpression Lysate (Adult Normal) [NBL1-13961] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PSGR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26173_PSGR%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13961-img0002.jpg)